Day 25 Flashcards

1
Q

Q1- Patient overall healthy presented with eye watery discharge, cloudy anteriorChamber with red conjunctiva, Diagnosis:

A-Keratitis
B-Uveitis
C-Retinitis
D-Corneal laceration

A

Ans: B

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2
Q

Q2-First line investigation for DVT (Deep vein thrombosis)

A-USG/duplex ultrasound
B-MRI
C-Venography
D-Nuclear imaging

A

Ans: A

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3
Q

Q3-A 70-year man with a history of hypertension and diabetes comes to the emergency department with a sudden onset of weakness in the right arm and leg over the last hour. On exam, he cannot lift the bottom half of the right side of his face. What is the best initial step?

A-Head CT with contrast
B-Head CT without contrast
C-Aspirin
D-Thrombolytics
E-MRI
A

Ans: B. Prior to administering thrombolytics or any anticoagulation, you need to rule out hemorrhagic stroke, which is a contraindication to thrombolytics. You cannot even give aspirin without doing a head CT first. Thrombolytics are indicated within the first 3 hours of the onset of the symptoms of a stroke. Remember, 20 percent of strokes are hemorrhagic. You do not need contrast to visualize blood; contrast is used to detect cancer or infection, such as an abscess.

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4
Q

Q4-A 47-year old man comes to the emergency department with fever, headache, photophobia, and a stiff neck. What is the next best step in the management of this patient?

A-Lumbar puncture
B-Head CT scan
C-Ceftriaxone and vancomycin
D-Penicillin
E-Movement of patient to ICU
A

Ans: A. When you suspect bacterial meningitis, administer antibiotics quickly. Further, do blood cultures stat simultaneously with a lumbar puncture (LP), or immediately prior. Penicillin can never be used as empiric therapy for meningitis; it is not sufficiently broad in coverage to be effective empiric therapy. In this case, perform the LP.

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5
Q

Q5-An elderly man comes to the emergency department with fever, headache, a stiff neck, and photophobia. He is HIV positive with < 50 CD4 cells and a history of pneumocystis pneumonia. His head CT is normal. CSF shows 2,500 white cells that are all neutrophils; Gram stain is normal. What is the best initial therapy?

A-Ceftriaxone and metronidazole
B-Cefoxitin and mefloquine
C-Ceftriaxone, ampicillin, and vancomycin
D-Fluconazole
E-Amphotericin
A

Ans: C. Listeria monocytogenes is a cause of meningitis that is not adequately treated by any form of cephalosporin. Ampicillin is added to the usual regimen of ceftriaxone and vancomycin to cover Listeria. This cannot be fungal meningitis, because the CSF is characterized exclusively by a high number of neutrophils; neutrophils are not consistent with fungal meningitis.

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6
Q

Q6-A 19 yearold male is brought to the emergency department with fever, headache, stiff neck, and photophobia. He has a petechial rash. CSF shows 2,499 neutrophils. Ceftriaxone and vancomycin are started. What should be done next?

A-Test for HIV
B-Wait for results of culture
C-Add ampicillin
D-Enforce respiratory isolation and prescribe rifampin for close contacts
E-Enforce respiratory isolation
A

Ans: D. When an adolescent present with a petechial rash and increased neutrophils on CSF, it is suggestive of Neisseria meningitidis. These patients should be placed on respiratory isolation, and close contacts should receive prophylaxis.

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7
Q

Q7-A 60 year old woman with metastatic breast cancer comes in with back pain. The spine is tender. She has hyperreflexia of the legs. What is the most urgent step?

A-X-ray
B-CT/ MRI
C-Biopsy
D-Radiation
E-Steroids
A

Ans: E. The most urgent step in the management of cord compression is to administer steroids as soon as possible and to relieve pressure on the cord. Imaging studies are done after steroids are given, if the diagnosis of cord compression is clear (as it is in this case with pain, tenderness, and signs of hyperreflexia in the legs).

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8
Q

Q8-A man comes to the emergency department with weakness in his legs that has been getting markedly worse over the last few days. He has weakness and loss of deep tendon reflexes in the legs. He recalls an upper respiratory illness about 2–4 weeks’ prior that resolved. What is the most urgent step?

A-Steroids
B-Intravenous immunoglobulins
C-Peak inspiratory pressure
D-Intubation
E-Lumbar puncture
A

Ans: C. This case is Guillain-Barré. Ascending weakness with loss of deep tendon reflexes is characteristic. Peak inspiratory pressure is the correct answer. The peak inspiratory pressure diminishes as the diaphragm is weakened. Peak inspiratory pressure predicts who will have respiratory failure before it happens. This is the most important factor in determining the need for therapy with either intravenous immunoglobulins(IVIG) or plasmapheresis. Combinations of these medications are not effective. Steroids are not effective. Lumbar puncture will show an elevated protein level with no cells.

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9
Q

Q9-Duration of drug in rheumatoid fever is?

A-6 years
B-15 years
C-Primary prevention lasts for 10 days and secondary prevention lasts for 5years or 10 years depending on presence of cardiatis

A

Ans: C

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10
Q

Q10-A patient is brought to the emergency department after a seizure leading to prolonged immobility on a sidewalk. He has dark urine and myalgias. What is the most urgent step in the management of this patient?

A-Urinalysis
B-Urine myoglobin level
C-EKG
D-CPK level
E-Phosphate level/S.Creatinine
A

Ans: C. EKG is the most urgent step in an acute case of rhabdomyolysis. This case tests your knowledge of how people die with rhabdomyolysis. Severe muscle necrosis leads to hyperkalemia, which leads to arrhythmia.A specific diagnosis with urinalysis or urine myoglobin is not as important as detecting and treating potentially life-threatening conditions, such as hyperkalemia with peaked T waves. This condition would be treated with immediate intravenous calcium gluconate, insulin, and glucose.

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11
Q

Q11-A 28-year-old man decides to donate a kidney to his brother, who is in chronic renal failure, after HLA typing suggests that he would be a suitable donor. He is admitted to the hospital, and his right kidney is removed and transplanted into his brother. Which of the following indices would be expected to be decreased in the donor after full recovery from the operation?

A-Creatinine clearance
B-Creatinine production
C-Daily excretion of sodium
D-Plasma creatinine concentration
E-Renal excretion of creatinine
A

Ans: A

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12
Q

Q12-Female with recently inserted IUCD coming with watery brownish vaginal discharge & abdominal painwhat is the most likely diagnosis?

A-Uterine rupture
B-Ovarian torsion
C-Bacterial vaginosis
D-Ectopic pregnancy

A

Ans: C

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13
Q

Q13-What is the best initial investigation in a postmenopausal woman with a breast lump?

A-Ultrasound
B-Mammography
C-MRI
D-Fine needle aspiration biopsy

A

Ans: A

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14
Q

Q14-65-year Hypertensive patient wakes up in morning with slurred speech, weakness of the left half of his body and drooling. Which part of the brain is affected?

A-Left parietal lobe
B-Right internal capsule
C-Right Midbrain
D-Left frontal lobe

A

Ans: B

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15
Q

Q15-A 25-year woman comes to sexual clinic and ask for advice for contraception. She is on sodium Valporate. (COCP= Combined Oral contraceptive pills)
COCP=combined oral contraceptive pills

A-She can use COCP
B-She can not use COCP
C-She can use COCP with extra precasution
D-She can use COCP with estrogen 50 microgrma and progesterone higher dose
E-She can use COCP if anti convulsant is changed to carbamezipine

A

Ans: A. Sodium valproate has no effect on COCP.

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16
Q

Q16-A 45-year woman has a 2-cm breast cancer tumor removed by lumpectomy, and the breast is irradiated. The cancer is negative for estrogen receptors and positive for progesterone receptors. Three of 14 nodes removed from the axilla are positive for cancer. What is the next best step in management?

A-Adjuvant chemotherapy and radiation of the axilla
B-Tamoxifen for 5 years
C-Anastrozole (aromatase inhibitor) for 5 years
D-Tamoxifen and adjuvant chemotherapy
E-Oophorectomy and chemotherapy

A

Ans: D. Tamoxifen is used whenever there are either estrogen receptors or progesterone receptors positive. If both receptors are positive, tamoxifen will be of greater benefit. Adjuvant chemotherapy is used whenever the axillary nodes are positive or the cancer is > 1 cm in size.

17
Q

Q17-Best test for diagnosis of adenomyosis

A-MRI
B-Hystroscopy
C-Ultrasound
D-Laproscopy

A

Ans: A

18
Q

Q18-Which beta blocker does not cause eractile dysfunction?

A-Atenolol
B-Timolol
C-Propanolol
D-Nebivolol
E-Acebutolol
A

Ans: D

19
Q

Q19-20year male with blood in urine on several ocassion since past year.each episode associates with respiratory or flu like symptoms.urine dipstick shows mild protinurea and micro hematuria. BUN normal. Serum IGA elevated. diagnosis

A-Berger disease
B-Good pasture
C-Minimal change disease
D-Post infectious Glomerulo nephritis
E-Wagner's Glomerulonephritis
A

Ans: A. 1. IgA nephropathy (Berger disease) It’s the most common glomerulonephritis.
Etiology: Abnormal IgA glycosylation; associated with infection and Henoch-Schönlein purpura; usually less than 30 years of age.
Diagnosis:
(1) Gross hematuria after 1-3 day’s URI or GI infection; no protein or WBC in the urine, normal (Nl). complements (BP may be Nl).
(2) Lab: Increased serum BUN, IgA, and renal deposits of IgA, IgG, and IgM (by immunostaining). Renal biopsy is the confirmative means of diagnosis.
Treatment : BP control; glucocorticoids +/- immunosuppressants help with acute flares. Prognosis: 80% of cases are good; 20% may progress to end-stage CRF.

20
Q

Q20-A man with prostate cancer presents with severe, sudden back pain. His MRI shows cord compression, and he is started on steroids. What is the next best step in management?

A-Flutamide
B-Flutamide and leuprolide simultaneously
C-Leuprolide followed by flutamide
D-Ketoconazole

A

Ans: A. Flutamide should be started first to block the temporary flare up in androgen levels that accompanies GnRH agonist treatments. When cord compression is described, GnRH agonists, if used too soon, can worsen the compression. Ketoconazole, at a high dose, blocks the production of androgens, but it is not as effective as the other therapies.

21
Q

Q21-A 24-year-old male with a history of gang violence presents to the emergency room with 3 stab wounds to the abdomen. He was intubated in the field for airway protection and is barely conscious. Blood pressure is 70/30 mm Hg and pulse is 140/min. On exam, 3 penetrating wounds covered by abdominal pressure pads are noted. Which of the following is the best next step in management of this patient?

A-Direct pressure to the abdomen
B-Abdominal x-ray
C-IV fluids
D-IV antibiotics
E-Obtain consent for surgery
A

Ans: C. This patient is in hemorrhagic shock and requires immediate resuscitation. Of the choices listed, the best next step in management is IV fluids after obtaining venous access. The best form of venous access is 2 large-bore IVs in the periphery and/or central venous access. Applying direct pressure to the abdomen (a) does not treat the underlying cause. Getting an abdominal x-ray (b) will take too long for a patient with this rateof blood loss. IV antibiotics (c) may be needed later in the care of this patient, but stabilizing blood pressure is now the more urgent need. Surgical consent (e) is implied in a life-threatening emergency in which a patient cannot communicate his wishes.

22
Q

Q22-8 weeks Primigravida came to you with nausea & vomiting, choose the statement that guide you to hyperemesis gravidarm

A-ketonia
B-ECG evidence of hypokalemia
C-Metabolic acidosis
D-Elevated liver enzyme
E-Jaundice
A

Ans: A

23
Q

Q23-Which of the following is not a sign or symptom of central retinal artery occlusion??

A-Painful loss of vision
B-Painless loss of vision
C-Previous transient loss of vision
D-Dilated pupil with sluggish reaction to light

A

Ans: A

24
Q

Q24-Cardiac disease with maximum maternal mortality in pregnancy

A-Eissenmenger syndrome
B-Uncorrected TOF (Teratology of Fallot)
C-Marfan syndrome with arotic dilatation
D-Mitral stenosis

A

Ans: A

25
Q

Q25-Which of the following is not a physiological change during pregnancy?

A-RBC volume 1.64L
B-Tidal volume 500ml
C-Cardiac output 6.5L/min
D-Uterus weight-1.1kg
E-ESR rise by 4 times
A

Ans: B