Day 2 - 2. Oxygen therapy, reanimation, euthanasia. Flashcards

1
Q

What does oxygen delivery depend on?

A
  • Hemoglobin conc -> Anemia
  • Oxygenisation of the arterial blood (PaO2) -> hypoxaemia
  • Cardiac output -> hemodynamic disturbance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the goal of oxygen delivery?

A

Increase the inspired O2 concentration (FiO2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the values of hypoxia?

A

Hypoxia (PaO2 < 80 Hgmm, Sa O2 <90%)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Clinical signs of hypoxia:

A
• Restlessness
• Dyspnoe
• Increased respiratiory rate (> 32-40/min)
• Labial breathing
• Open mouth breathing (cats)
• Abnormal respiratory sounds
– Upper airway stridor
– Crepitaion
– Respiration 0 (pleural effusion, pneumothorax)
• Cyanosis
• Gasping
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which sedation is used during hypoxia?

A

Acepromazin
Butorphanol
Midazolam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the common causes of hypoxia?

A
  1. Upper respiratory obstruction
  2. Pulmonary diseases
  3. Congestive heart failure
  4. Pleural effusion
  5. Thoracic trauma (pneumothorax, lung contusion)
  6. Inhalation of toxic gases (smoke, CO)
  7. Severe anaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are some Upper respiratory obstructions?

A

– Brachycephal syndroma
– laryngeal collapse
– Laryngeal paralysis
– Tracheal collapse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Give some pulmonary diseases:

A

– Pneumonia

– Pulmonary edema/ARDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are used for the arterial blood gas analysis?

A
  1. Femoral or metatarsal arteries
  2. PaO2
  3. SatO2
  4. PaCO2
  5. A-a gradient
  6. „Rule of 120”
  7. PaO2/FiO2 ratio
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Explain A-a gradient:

A

difference between alveolar O2 pressure and PaO2 (<10-15)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Explain rule of 120:

A

PaO2 + PaCO2, if < 120→V/Q-mismatch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the normal , acute lung injury and ARDS values of : PaO2/FiO2 ratio

A
  • Normal: > 400 Hypoxaemia: 300-400
  • Acute Lung Injury: 200-300
  • Acute Respiratory Distress Syndrome < 200
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Oxygen sources:

A
  1. Bottle or concentrator
  2. „Flow by” oxygen
  3. Oxygen hood / collar
  4. Nasal oxygen catheter
  5. Oxygene cage
  6. Endotracheal tube
  7. Mechanical ventilation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Explain „Flow by” oxygen:

A

„Flow by” oxygen

  • Small diameter tube held to the nose of the patient
  • Through mask→some animals don’t tolerate
  • 2-3 liter/min→FiO2: 25-40%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Explain Oxygen hood / collar:

A

Oxygen hood / collar
• Elisabeth collar ventral 50-75% covered by plastic folia
• 1 liter/10 kg/min→FiO2: 40-60%
• CAVE: some dogs do not tolerate it – panting→ increased humidity → hyperthermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Explain Nasal oxygen catheter:

A

Nasal oxygen catheter
Thin (6-9Fr) plastic tube placed in the ventral meatus of the nose
Well tolerated on long term management
50-100 ml/kg/min→FiO2: 40-50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Explain oxygen cage:

A
Oxygene cage
• Floading over 20 minutes
• FiO2: 30-50%
• Safe use in long term management
• Lack of stress
• CAVE panting → increased humidity → hyperthermia, CO2 
• Expensive!!
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Explain Endotracheal tube:

A

Endotracheal tube
Primarily in upper respiratory tract obstructions perioperatively
Anesthesia required
FiO2: 21-100%

19
Q

What are the mechanical ventilation – indications:

A

Mechanical ventilation – indications:

  • Severe hypoxia (PO2<60 mmHg)
  • Sever hypercapnia (PCO2 >60 mmHg)
  • Excessive work of breathing
20
Q

CPCR =

A

Cardiopulmonary cerebral resuscitation

21
Q

When is CPCR performed?

A

cardiorespiratory arrest (CPA)

22
Q

Clinical signs of CPA

A
– Gasping / agonial breathing pattern 
– unconciousness
– Lack of spontaneous breathing
– Lack of palpable pulse
– Lack of cardiac sounds
23
Q

When is the prognosis poor?

A

< 10% ROSC

<1% survive to discharge

24
Q

Potentially reversible causes of CPA:

A

5 H, 5T

25
Q

Give the 5 H

A
  1. Hypovolaemia/haemorrhage
  2. Hypoxia/hypoventilation
  3. Hydrogen ions –> acidosis
  4. Hyperkalaemia/hypokalaemia
  5. Hypoglycaemia
26
Q

Give the 5 T

A
  1. Toxina
  2. Tension pneumothorax
  3. Thromboembolism
  4. Tamponade (pericardial)
  5. Trauma
27
Q

Parameters of monitoring a critically ill patient:

A

T,P,RR,CRT, BG

28
Q

Common causes of critical patients:

A
– SIRS (systemic inflammatory response syndrome)
– septikaemia
– Congestiveheartfailure
– Severe respiratory disease, ARDS
– Cerebraldiseases(seizures),
– Multipletrauma
–coagulopathia, toxicosis, anaesthesia
– Ill puppies BW< 2 kg!!!
29
Q

Things to consider before CRCP…

A
  • Underlying disease…
  • Owners will
  • Timing – within 3-5 minutes after CPA
  • Equipment
  • Trained staff (3+n)
30
Q

The ABC of cardiopulmonary resuscitation

A

Airways
Breathing
Circulation

Drugs
ECG
Fluids

31
Q

Airways

A

– Clean the airways (mucose, FB)

– Endotracheal intubation

32
Q

Breathing

A

with AMBU-ballon 10-12/min rate

33
Q

Circulation

A

Thoracic compressions
Right lateral recumbency
Position of the hands:
– Medium- large breed: both hands on the widest points of the thorax
– Medium breeds: one handover the heart(4-6. intercostal space)
– Small breeds and cats: 1 handover the cardiac area, thumb on the other side of the chest

34
Q

Drugs

A

• Drug applications
– Intravenous
– Intratracheal
• safe: atropin, epinephrine/adrenalin, lidokain, naloxon, vazopressin
• 2-2,5x dose is necessary (epinephrine: 3-10x IV dosage!)
• Drug should be solved in 5-10 ml sterile water or saline
• CAVE: severe pulmonary disease (edema)

35
Q

ECG

A
Background – Asystole
– Electric activity without pulse
– Ventricular tachycardia
Ventricular fibrillation
Severe sinusbradycardia
36
Q

Fluids

A

• Patients with hypovolaemia: shock dosis
– crystalloids: dog: 90 ml/kg, cat: 45 ml/kg
– Colloids (HAES) dog: 5 ml/kg cat: 2-3 ml/kg
– Hypertonic saline: NaCl (3%)

  • Patients with euvolemia: crystalloids in bolus with maximum speed
  • dog: 20 ml/kg bolus
  • cat: 10 ml/kg bolus
37
Q

Commonly used drugs (ABC)

A

Adrenalin (Tonogen inj)
• mainly alpha2 adrenergic stimulatory effect:
peripheral arteriolar vasoconstriction increase → cerebral and coronarial perfusion pressure increase
• 0,01mg/kgIV
• Dosage can be repeated in 3-5 min (max: 0.1 mg/kg IV)

Atropin (Atropin inj.)
– Heart rate increase, vascular resistance increase, blood pressure increase
– Most effective in case of vagotonia induced asystole
– 0,04 mg/kg IV
– Can be repeated in 3-5 minutes 3x

38
Q

When is it allowed to use euthanasia?

A

-Incurable disease or injury
– Control of infectious diseases – Unavertable attack
– Scientific research
– (high treatment costs)

39
Q

Parameters of quality of life:

A
• Pain (1-10)
• Appetite (1-10)
• Hydration (1-10)
• Hygine (1-10)
• Mood (1-10)
• Locomotion (1-10)
• More „good than bad days”(1-10)
>35: acceptable QOL
40
Q

Describe the procedure of euthanasia:

A
  • Place i.v. catheter
  • General anesthesia – (acepromazin/ ketamin+diazepam/ propofol) i.v.
  • Drugs for euthanasia – Pentobarbital60-100mg/ttkg:
  • Release inj (1 ml/5ttkg)
  • Euthasol 40 % inj. – T-61inj.0,3ml/ttkg(?)
41
Q

What can be done if the iv catheterisation is not possible in case of euthanasia?

A

→ induce anesthesia i.m. →apply euthanasia medication i.c.

• Monitor heart, respiration, corneal reflexes

42
Q

Mistakes of euthanasia :

A
  • Let the patient wait for long in the waiting room
  • Leave the cadaver alone in the treatment room
  • Handle the body without respect
  • Underestimate the grief of the owner
  • Recommend to buy/get a new animal
43
Q

As a vet, how should you act when performing an euthanasia?

A

Circumstances: empathy, empathy, empathy
• Quiet room (turn off cell phones!)

• According to the wish of the owner:
– Wish to say goodbye? (left few minutes alone)
– Wish to be present?
– What happens with the

• Prepare what will happen… describe the procedure
– i.v. catheter
– Induce anesthesia
– Apply drug for euthanasia
– May void urine or feces
– Possible unvoluntary muscle constrictions