Day 1 Chromosomal Abnormalities 1

Question 1

1. Describe the events in meiosis that produce genetic variability among offspring.

Answer 1

1) Independent Assortment of maternal and paternal chromosomes
2) (Recombination during Meiotic Prophase 1): Crossing Over: During prophase 1 of meiosis 1, homologous pair of chromosomes cross over and often share genetic information, creates diversity by allowing genes from each parent to intermix, thus resulting in new genetic complement

Question 2

2. Compare and contrast mitotic and meiotic cell divisions.

Answer 2

Mitotic: 1 div
Meiotic: 2 div
Both have replication cycle

Question 3

4. Describe the clinical features of common human trisomies: 21, 18, and 13.

Answer 3

18: Trisomy: small for gestational age, microencephaly, clenched hand/overlapped fingers, rocker bottom feet, heart/brain abnormalities
21: Trisomy: Down Syndrome: