Data Interpretation Flashcards
Causes of hyponatraemia?
Hypovolaemic:
- Fluid loss (esp diarrhoea/vom)
- Addison’s
- Diuretics
Euvolemic:
- SIADH
- Psychogenic polydipsia
- Hypothyroidism
Hypervolemic:
- HF
- Renal failure
- Liver failure
- Nutritional failure
- Thyroid failure
Causes of hypernatraemia?
- Dehydration drips (e.g. too much saline)
- Drugs
- Diabetes insipidus
Causes of hypokalaemia?
DIRE
Drugs (loop + thiazide)
Inadequate intake or intestinal loss (D+V)
Renal tubular acidosis
Endocrine (cushings/conns)
Causes of hyperkalemia?
DREAD
Drugs (K sparing diuretics + ACEi)
Renal failure
Endocrine (addisons)
Artefact (quite common)
DKA
Biochemical disturbance for prerenal AKI?
Urea rise»_space;> Creatinine rise
Biochemical disturbance for intrinsic renal AKI?
Urea rise «< Creatinine rise
Bladder or hydronephrosis not palpable
Biochemical disturbance for post renal AKI?
Urea rise «< Creatinine rise
Bladder/hydronephrosis may be palpable
Causes of pre-renal AKI?
Dehydration (or if severe, shock)
Renal artery stenosis
Causes of intrinsic renal AKI?
INTRINSIC
Ischaemia
Nephrotoxic abx (gent, vanc, tetracyclines)
Tablets (ACEi, NSAIDs)
Radiological contrast
Injury (rhabdomyolysis)
Negatively birefringent crystals (gout)
Syndromes (glomerulonephritis)
Inflammation (vasculitis)
Cholesterol emboli
Causes of post renal AKI?
In lumen:
- stone or sloughed papilla
In wall:
- tumour
External pressure:
- BPH
- Prostate cancer
- Lymphadenopathy
- Aneurysm
Signs of digoxin toxicity?
Confusion
Nausea
Visual halos
Arrhythmias
Signs of lithium toxicity?
Early: tremor
Intermediate: tiredness
Late: arrhythmias, seizures, coma, renal failure, diabetes insipidus
Signs of phenytoin toxicity?
Gum hypertrophy
Ataxia
Nystagmus
Peripheral neuropathy
Teratogenicity
Signs of gentamicin toxicity?
Ototoxicity and nephrotoxicity
Signs of vancomycin toxicity?
Ototoxicity and nephrotoxicity