cytotoxic drugs

Question 1

drug handling

Answer 1

reconstituted by trained personnel
reconstituted in designated pharmacy areas
wear protective clothing
use eye protection
avoided by pregnant staff (females of childbearing age informed of hazard)
use local procedures for spillages, safe disposal, syringes, containers etc.
monitor staff exposure to cytotoxins

Question 2

drug classes

Answer 2

alkylating agents - cyclophosphamide, ifosfamide, melphalan

anthracyclines - daunorubicin, doxorubicin, epirubacin, idarubicin

anti-metabolites - cytarabine, fluorouracil, methotrexate, mercaptopurine

cytotoxic antibiotics - bleomycin, mitomycin

plantinum compounds - carboplatin, cisplatin, oxaliplatin

taxanes - carbazitaxel, docetaxel, paclitaxel

vinca alkaloids - vinblastine, vincristine, vindesine