Cytomegalovirus (CMV) Flashcards
1
Q
CMV is the most common cause of which deformations?
A
Congenital defects
2
Q
CMV is the second most common causative agent of…?
A
Mental handicap after Down Syndrome
3
Q
Which body fluid has the highest CMV titer?
A
semen
4
Q
what is the classic cytopathological finding of CMV infected cells?
A
Owl’s eye (enlarged cells with inclusion bodies)
5
Q
What kind of genome does CMV have?
A
class E genome (most complicated)
6
Q
How does CMV infection differ from EBV infection?
A
CMV does not affect B lymphocytes neither does it cause their proliferation resulting in absence of heterophile antibodies in CMV mononucleosis-like syndrome
7
Q
Most of the CMV antibodies are directed against which specific molecule?
A
glycoprotein gB
