Cytomegalovirus Flashcards
1
Q
what appearance do cells infected with cytomegalovirus have?
A
‘owl’s eye’ appearance due to intranuclear inclusion bodies
2
Q
patterns of disease
congenital CMV infection
A
- growth retardation
- pinpoint petechial ‘blueberry muffin’ skin lesions
- microcephaly
- sensorineural deafness
- encephalitiis (seizures)
- hepatosplenomegaly
3
Q
patterns of disease
CMV mononucleosis
A
- infectious mononucleosis-like illness
- may develop in immunocompetent individuals
4
Q
patterns of disease
CMV retinitis
A
- common in HIV with low CD4
- ‘blurred vision’
- fundoscopy = retinal haemorrhages and necrosis (called ‘pizza’ retina)
- IV ganciclovir is treatment of choice
