Cytokines, wound healing Flashcards

0
Q

Wound healing day 0-2

A

Neutrophils

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1
Q

Cachexia

A

TNF- alpha

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2
Q

Wound healing day 3-4

A

Macrophage

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3
Q

Wound healing day 0-2

A

Fibroblast

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4
Q

Wound healing growth factor

A

PDGF

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5
Q

Fever

A

IL-1

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6
Q

Acute phase reactants

A

IL-6

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7
Q

Angiogenesis, PMN chemotaxis

A

IL-8

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8
Q

Decreases inflamm rxn (cytokine)

A

IL-10

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9
Q

Immunosuppressive growth factor

A

TGF beta

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10
Q

Hepatic proteins decreased by inflammation

A

Albumin
Prealbumin
Transferrin

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11
Q

PGI2

A

Vasodilation and bronchodilation

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12
Q

PGE2

A

Vasodilation and bronchodilation

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13
Q

TXA2

A

Vasoconstriction, platelet aggregation

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14
Q

Leukotrienes

A

Bronchoconstriction and vasoconstriction

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15
Q

When does wound contraction occur?

A

10-15 days

16
Q

Max collagen synthesis

A

3 weeks

17
Q

Max tensile strength

A

8 weeks