Cytokines Part 1 Flashcards
1
Q
IL-1 Description
A
Inflammatory Cytokine
: IL-1α
: IL-1ß
: IL-1RA
2
Q
TNF Description
A
Inflammatory Cytokine
: For G(-) Bacteria
: Stimulates gene transcription
: Induces apoptosis
3
Q
TNF-α forms and effects
A
Soluble Form
Membrane-bound Form
Vasodilation + Vasopermeability
4
Q
IL-6 Description
A
Cytokine Cascade
: Triggered by IL-1
: Secreted by lymphoid & non-lymphoid cells
5
Q
IL-6 Functions
A
Inflammation
: Acute phase reactions
Immunoglobulin Secretion
: Activation of B&T Cells
: Activation for B into Plasma Cells
6
Q
Chemokine Function
A
Motility
Migration
Chemotaxis
7
Q
TGF-ß Function
A
Antiproliferative activity