Cytokines Part 1 Flashcards

1
Q

IL-1 Description

A

Inflammatory Cytokine
: IL-1α
: IL-1ß

: IL-1RA

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2
Q

TNF Description

A

Inflammatory Cytokine
: For G(-) Bacteria
: Stimulates gene transcription
: Induces apoptosis

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3
Q

TNF-α forms and effects

A

Soluble Form
Membrane-bound Form
Vasodilation + Vasopermeability

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4
Q

IL-6 Description

A

Cytokine Cascade
: Triggered by IL-1
: Secreted by lymphoid & non-lymphoid cells

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5
Q

IL-6 Functions

A

Inflammation
: Acute phase reactions
Immunoglobulin Secretion
: Activation of B&T Cells
: Activation for B into Plasma Cells

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6
Q

Chemokine Function

A

Motility
Migration
Chemotaxis

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7
Q

TGF-ß Function

A

Antiproliferative activity

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