cytokines Flashcards
1
Q
Il-1
A
Innate
Mono, Macro, eno, epi
Inflam, fever, APP
2
Q
TNF-a
A
Innate
Macro
Inflam, APP, cachexia, apoptosis, neutro +
3
Q
IL-12
A
Innate
Macro, Dendritic
NK, + Th1 in adaptive
4
Q
IL-6
A
Innate
Macro, endo
APP, B cell AB secretion +
5
Q
IFN-a
A
Innate
Macro
+antiviral state, + MHC1 expression, +NK cells
6
Q
IFN-b
A
Innate
Fibroblast
+antiviral state, + MHC1 expression, +NK cells
7
Q
IL-2
A
Adaptive
T cells
Tcell proliferation, +NK , + Bcell proliferation
8
Q
IL-4
A
Adaptive
Th2, mast
Th2 differentiation, Isotype switching to IgE
9
Q
IL-5
A
Adaptive
Th2
Eosino +
10
Q
TGF-b
A
Adaptive
Tcell,macro, others
INHIBITS T-cell/B-cell proliferation, inhibits macrophages, isotype switch to IgA
11
Q
IFN-y
A
Adaptive
Th1, CD8+, NK
+macro, + MHC1 and 2 expression, + Ag presentation
