Cytokines Flashcards
Main cell source of: IFN-γ
Th1, NK and NKT cells
Main cell source of: IL1
Monocytes and activated macrophages
Main cell source of: IL2
Th1 Cells
Main cell source of: IL4
TH2 Cells
Main cell source of: IL6
Monocytes and activated macrophages
Main cell source of: IL8
Monocytes and activated macrophages
Main cell source of: IL10
Dendritic cells, Monocytes and activated macrophages, Th2 and Tregs
Main cell source of: IL12
Monocytes and activated macrophages, Dendritic cells
Main cell source of: IL21
Th1, Th2 and Th17
Main cell source of: IL23
Dendritic cells, Monocytes and activated macrophages
Main cell source of: TNF-α
Dendritic cells, Monocytes and activated macrophages
Main cell source of: TGF-β
Many cells
Major function of: IFN-γ
TMMI, inhibits Th17
Major function of: IL1
Pro-inflammatory
Major function of: IL2
T cell proliferation, Treg survival
Major function of: IL4
Antibody immunity, inhibit Th17
Major function of: IL6
Innate immunity, B cell growth, induction of Th17
Major function of: IL8
Pro-inflammatory, major neutrophil chemokine
Major function of: IL10
Suppression of some inflammatory pathways
Major function of: IL12
Induction of Th1
Major function of: IL21
Proliferation of Th1, Th2 and Th17
Major function of: IL23
Th17 expansion and stabilization
Major function of: TNF-α
Pro-inflammatory
Major function of: TGF-β
Induction of Tregs of Th17
