Cytogenetics Flashcards
1
Q
t(14;18)
A
Follicular lymphoma
-BCL2-IgH
= B-cell germinal center lymphocytic lymphoma
-type of small B-cell lymphoma
2
Q
t(11;14)
A
Mantle cell lymphoma
- BCL1-IgH
- type of small B-cell lymphoma
3
Q
t(8;14)
A
Burkitt’s lymphoma
- c-myc-IgH
- aggressive B cell lymphocytic leukemia
4
Q
t(15;17)
A
APL (acute promyelocytic leukemia)
-PML-RARalpha
5
Q
t(8;21)
A
AML
6
Q
t(9;22)
A
CML
- BCR-ABL
- Philadelphia chromosome
7
Q
t(12;21)
A
ALL (acute lymphocytic leukemia)
8
Q
Molecular typing of follicular lymphoma
A
CD20(+) CD10(+)
9
Q
Molecular typing of mantle cell
A
CD 20 (+) CD5(+)
10
Q
Molecular typing of MALT
A
CD20 (+) everything else (-)
11
Q
Molecular typing of Burkitt’s
A
CD20 (+) CD10 (+)
12
Q
CLL molecular typing
A
CD20 (+) CD5 (+) CD23 (+)
13
Q
Hairy cell molecular typing
A
CD20 (+) CD103 (+)
