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PHA-2048 > cytochromes p450 et substrats et inhibiteurs > Flashcards

cytochromes p450 et substrats et inhibiteurs Flashcards

1
Q

What classes of drugs are 1A2 substrates?

A

antidepressants, antipsychotics

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2
Q

What classes of drugs are 2C8 substrates?

A

glithazones

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3
Q

What classes of drugs are 2C9 substrates?

A

antidepressants, angiotensin II blockers, hypoglycemics, and NSAIDs

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4
Q

What classes of drugs are 2C19 substrates?

A

antidepressants, proton pump inhibitors

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5
Q

What classes of drugs are 2D6 substrates?

A

antidepressants, antipsychotics, analgesics, CV drugs

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6
Q

What classes of drugs are 2E1 substrates?

A

anesthetics

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7
Q

Name 3/18 classes of drugs that are 3A4 substrates.

A

antidepressants, antipsychotics, sedative-hypnotics

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8
Q

Name 3-6/18 classes of drugs that are 3A4 substrates.

A

analgesics, antiarrythmetics, antibiotics

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9
Q

Name 6-9/18 classes of drugs that are 3A4 substrates.

A

anti-epileptics, antimalarials, antineoplasics

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10
Q

Name 9-12/18 classes of drugs that are 3A4 substrates.

A

antiparkinsonian, antirejection, Ca-channel blockers

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11
Q

Name 12-15/18 classes of drugs that are 3A4 substrates.

A

statins, macrolide ABs, nonnucleoside reverse transcriptase

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12
Q

Name 15-18/18 classes of drugs that are 3A4 substrates.

A

protease inhibitor, steroids, triptans

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13
Q

What drugs are inhibitors of CYP 1A2?

A

fluvoxamine, ciprofloxacine, méxilétine, propafénone

Votre ami a eu le flu, car acine a flex comme un pro, il a été late pour le Méxique. None a fait propager la COVID.

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14
Q

What drugs are inhibitors of CYP 2C9?

A

fluvoxamine, fluconazole, ritonoavir, sulfaphénazole

Votre ami a eu le flu, car il était con et seul. Il rit de ton navire, et du fat phénomène azole.

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15
Q

What drugs are inhibitors of CYP 2C19?

A

fluvoxamine, ticlopidine

Votre ami a eu le flu, et donc les pieds qui tickle.

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16
Q

What drugs are inhibitors of CYP 3A4?

A

quinidine, ritonavir, fluoxétine, norfluoxétine, paroxétine, bupropion, cimétidine

C’est qui Nidine? Il rit de ton navire. Oxétine a eu le flu au nord. Elle a subi un paradoxe et a bu son propre ion. Then, she met Idine.

PHA-2048 (1 decks)

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