Cytochrome P450 Flashcards

1
Q

CPY1A2

A

substrates: acetaminophen, caffeine, theophylline
inducers: smoking

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2
Q

CPY2A6

A

substrates: zidovudine, warfarin

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3
Q

CPY2C9

A

substrates: hexobarbital, ibuprofen, phenytoin, S-warfarin
inducers: rifampin

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4
Q

CPY2D6

A

substrates: amitriptyline (antidepressant), codeine, fluoxetine, timolol, hydrocodone

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5
Q

CPY2E1

A

substrates: acetaminophen, ethanol
inducers: ethanol

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6
Q

CPY3A4

A

substrates: amiodarone, benzos, calcium channel blockers, erthromycin, steroids (cortisol)
inducers: phenytoin, rifampin

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7
Q

CYP2C19

A

substrates: diazepam, omeprazole, propranolol

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