Cytochrome P450 Flashcards
1
Q
CPY1A2
A
substrates: acetaminophen, caffeine, theophylline
inducers: smoking
2
Q
CPY2A6
A
substrates: zidovudine, warfarin
3
Q
CPY2C9
A
substrates: hexobarbital, ibuprofen, phenytoin, S-warfarin
inducers: rifampin
4
Q
CPY2D6
A
substrates: amitriptyline (antidepressant), codeine, fluoxetine, timolol, hydrocodone
5
Q
CPY2E1
A
substrates: acetaminophen, ethanol
inducers: ethanol
6
Q
CPY3A4
A
substrates: amiodarone, benzos, calcium channel blockers, erthromycin, steroids (cortisol)
inducers: phenytoin, rifampin
7
Q
CYP2C19
A
substrates: diazepam, omeprazole, propranolol