Cytochrome P450 Flashcards

1
Q

what kind of reactions do cytochrome p450s carry out?

A

Key hydroxylation reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is another name for P450s?

A

MFOs (mixed function oxygenases)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are all cytochromes generally composed of?

A

A protein plus a redox active heme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What type of heme is in cyto p450?

A

b-type heme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What does the heme part of cytochromes catalyze?

A

Electron transport between substrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Why is the heme a good electron carrier?

A

Fe is redox active.

pi structure of heme allows electron to be delocalized into heme ring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly