Cytochrome P-450 Interactions (Selected) Flashcards

1
Q

Anti-epileptics

A

Substrate

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2
Q

Phenobarbital

A

Inducer

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3
Q

Acute EtOH abuse

A

Inhibitor

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4
Q

Chronic EtOH use

A

Inducer

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5
Q

Griseofulvin

A

Inducer

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6
Q

Theophylline

A

Substrate

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7
Q

Carbamazepine

A

Inducer

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8
Q

Ketoconazole

A

Inhibitor

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9
Q

Chloramphenicol

A

Inhibitor

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10
Q

Phenytoin

A

Inducer

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11
Q

Cimetidine

A

Inhibitor

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12
Q

Omeprazole

A

Inhibitor

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13
Q

Sulfonamides

A

Inhibitor

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14
Q

Valproate

A

Inhibitor

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15
Q

Erythromycin (macrolides except azithromycin)

A

Inhibitor

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16
Q

Metronidazole

A

Inhibitor

17
Q

Verapamil

A

Inhibitor

18
Q

Warfarin

A

Substrate

19
Q

Ciprofloxacin

A

Inhibitor

20
Q

Nevirapine

A

Inducer

21
Q

OCPs

A

Substrate

22
Q

Fluconazole

A

Inhibitor

23
Q

Rifampin

A

Inducer

24
Q

St. John’s wort

A

Inducer

25
Q

Isoniazid

A

Inhibitor