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Pharm > Cytochrome P-450 Interactions > Flashcards

Cytochrome P-450 Interactions Flashcards

1
Q

Inducers (+)

A 
Chronic alcohol use 
Modafinil
St. John’s wort 
Phenytoin 
Phenobarbital 
Nevirapine 
Rifampin 
Griseofulvin 
Carbamazepine

“Chronic alcoholic Mona Steals Phen-Phen and Never Refuses Greasy Carbs”

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2
Q

Substrates

A 
Anti-epileptics 
Antidepressants
Antipsychotics 
Anesthetics 
Theophylline 
Warfarin 
Statins
OCPs
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3
Q

Inhibitors (-)

A 
Acute alcohol abuse 
Gemfibrozil 
Ciprofloxacin 
Isoniazid 
Grapefruit juice 
Quinidine 
Amiodarone 
Ketoconazole 
Macrolides 
Sulfonamides 
Cimetidine 
Ritonavir
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4
Q

Inducer or Inhibitor?

Chronic OH

A

Inducer

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5
Q

Inducer or Inhibitor?

Modafinil

A

Inducer

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6
Q

Inducer or Inhibitor?

St. John’s wart

A

Inducer

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7
Q

Inducer or Inhibitor?

Phenytoin

A

Inducer

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8
Q

Inducer or Inhibitor?

Phenobarbital

A

Inducer

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9
Q

Inducer or Inhibitor?

Nevirapine

A

Inducer

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10
Q

Inducer or Inhibitor?

Rifampin

A

Inducer

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11
Q

Inducer or Inhibitor?

Griseofulvin

A

Inducer

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12
Q

Inducer or Inhibitor?

Carbamazepine

A

Inducer

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13
Q

Inducer or Inhibitor?

Acute OH

A

Inhibitor

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14
Q

Inducer or Inhibitor?

Gemfibrozil

A

Inhibitor

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15
Q

Inducer or Inhibitor?

Ciprofloxacin

A

Inhibitor

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16
Q

Inducer or Inhibitor?

Isoniazid

A

Inhibitor

17
Q

Inducer or Inhibitor?

Grapefruit juice

A

Inhibitor

18
Q

Inducer or Inhibitor?

Quinidine

A

Inhibitor

19
Q

Inducer or Inhibitor?

Amiodarone

A

Inhibitor

20
Q

Inducer or Inhibitor?

Ketoconazole

A

Inhibitor

21
Q

Inducer or Inhibitor?

Macrolides

A

Inhibitor

22
Q

Inducer or Inhibitor?

Sulfonamides

A

Inhibitor

23
Q

Inducer or Inhibitor?

Cimetidine

A

Inhibitor

24
Q

Inducer or Inhibitor?

Ritonavir

A

Inhibitor

Pharm (4 decks)

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