Cytochemistry Flashcards
1
Q
Specific esterase
What is it positive in
A
Positive in myeloid cells
In AMML myeloblasts are red with specific
2
Q
Non specific esterase
A
Positive in monocytes
In AMML, monoblasts are blue with nonspecific
3
Q
Periodic Acid Schiff (PAS)
What is positive, what is negative?
A
Positive in lymphoblasts (ALL) and erythroblasts (AEL, DiGuglielmo’s)
Normal erythroblasts will be negative
4
Q
Leukocyte Alkaline Phosphatase (LAP)
A
Positive in leukemoid reactions
NOT in neoplasms, NOT in CML
5
Q
Tartrate Resistant Acid Phosphatase (TRAP)
A
Positive in hairy cells
6
Q
Terminal Deoxynucleotidal Transferase (TdT)
Method of interpretation?
A
Positive in most acute lymphocytic leukemia ALL
Interpreted with immunofluorescence