Cysts of Jaws Flashcards

1
Q

What is a cyst?

A
  • Pathological cavity having fluid, semi-fluid or gaseous contents , not created by accumulation of pus
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2
Q

What are the key features of cysts that can be used to describe a cystic lesion?

A

Asymptomatic or symptomatic
Slow growing or fast growing
Indolent (lazy) or destructive
Almost all are benign

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3
Q

What radiographic investigations can be utilised in cystic diagnoses?

A

Initial
- PA
- Occlusal radiograph
- Panoramic

Supplemental
- Cone beam CT
- Facial radio like PA mandible view, occipitomental view

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4
Q

Give some Clinical features of cystic lesions

A
  • Discolouration superficial area
  • Loss of vitality and mobility of ass teeth
  • May be hard at first then soft to touch (egg shell crackling) *** key to cystic lesion
  • Usually slow growing
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5
Q

Describe this picture

A
  • Blueish colour
  • Swelling
  • Absence of 21
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6
Q

Describe this lesion

A
  • Dark Discolouration on labial surface of gingivae between 31 and 32
  • Swelling
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7
Q

When you are describing a cystic lesion from a radiograph what must you include? (7)

A
  • Location
  • Shape (often spherical or egg shaped)
  • Margins (Often well defined and corticated)
  • Locularity (Often unilocular but can be multilocular or pseudolocular)
  • Multiplicity (single, bilateral or multiple)
  • Effect on surrounding anatomy (displacement of cortical plates, adjacent teeth, max sinus, IANC - variable degree and pattern of growth - root resorption from chronic)
  • Inclusion of unerupted teeth
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8
Q

What can multiple cysts indicate?

A
  • A syndrome
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9
Q

if a cyst is secondarily infected what can this change about appearance?

A
  • Lose definition
  • Los cortication of margins
  • Ass with clinical signs and symptoms
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10
Q

What are the 3 categories that cysts can be classified into?

A

Structure
- Epithelium lined vs no epithelial lining

Origin
- odontogenic vs non-odontogenic

Pathogenesis
- Developmental vs inflammatory

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11
Q

If a cysts if odontogenic in nature it can be developmental or inflammatory. Give developmental cysts and give Inflammatory cysts

A

Developmental
- Dentigerous cyst (eruption cyst)
- Odontogenic keratocyte
- Lateral periodontal cyst

Inflammatory
- Radicular cyst (residual cyst)
- Inflammatory collateral cysts either Paradental cyst or Buccal bifurcation cyst

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12
Q

Give non-odontogenic cysts

A

Developmental
- Nasopalatine duct cyst

Other
- Solitary bone cyst
- Aneurysmal bone cyst
(both other have no epithelial lining)

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13
Q

Give the odontogenic sources of epithelium

A

Rests of Malassez
- Remnants of Hertwig’s epithelial root sheath

Rests of Serres
- Remnants of dental lamina

Reduced enamel epithelium
- Remnants of enamel organ

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14
Q

Give the epidemiology and incidence of odontogenic cysts

A
  • Occur in tooth bearing areas
  • All lined with epithelium
  • Most common cause of bony swelling in jaws
  • > 90% of all cysts in oral and maxillofacial region
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15
Q

Give the 3 most common odontogenic cysts and their prevalence

A
  1. Radicular cyst (residual cyst) approx 60% of odontogenic cysts
  2. Dentigerous cyst (eruption cyst)
    approx 18%
  3. Odontogenic Keratocyst
    approx 12% in maxillofacial region
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16
Q

What is a radicular cyst? How do they occur?

A
  • Inflammatory odontogenic cyst
  • Always ass with non-vital tooth
  • Initiated by chronic inflammation at apex of tooth due to pulp necrosis
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17
Q

What is the incidence of radicular cysts?

A

Most common 40/50
Equal in male and female
60% maxilla 40% mandible
Can involve any tooth

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18
Q

What is the presentation of radicular cyst?

A
  • Often asymptomatic but when it is infected can cause pain
  • Slow growing with lim expansion
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19
Q

Give the stages of non vital tooth becoming a radicular cyst

A
  • Non vital tooth
  • Pulpal necrosis
  • Periapical periodontitis
  • Periapical granuloma
  • Radicular cysts
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20
Q

Give the difference of radicular cysts to periapical granulomas

A
  • hard to differentiate radiographically but
  • Radicular cysts larger so
    if radiolucency >15mm then 2/3rds of cases it is radicular cyst and not PA granuloma
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21
Q

What can cause numbness

A
  • Trauma
  • Infection
  • Cyst
  • Tumour (benign or malignant)
  • TN
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22
Q

What is a residual cyst?

A
  • When radicular cyst persists after loss of tooth (or after tooth successfully RCT)
  • Avoid misdiagnosis so be thorough with history - recent XLA
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23
Q

What is a lateral radicular cyst?

A
  • Radicular cyst ass with accesory canal
  • located at side of tooth instead of apex
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24
Q

What is a inflammatory collateral cyst? What cysts does it include?

A
  • Inflammatory odontogenic cyst
  • Ass with vital tooth
  • 2-7% odontogenic cysts

Collective term for
- Paradental cysts
- Buccal bifurcation cyst

25
Q

What is a paradental cyst?

A
  • Typ occurs at distal aspect of partially erupted mandibular third molar
26
Q

What is a Buccal bifurcation cyst?

A
  • Typ occurs at buccal aspect of mandibular third molar
27
Q

Give some examples non-odontogenic examples

A
  • Nasopalatine duct cyst (most common)
  • Solitary bone cyst
  • Aneurysmal bone cyst
28
Q

What is a nasopalatine duct cyst? Give the incidence. What is it AKA?

A
  • Developmental non odontogenic cyst
  • Arises form nasopalatine duct epithelial remnants
  • Occurs in anterior maxilla

Incidence
- most comm 40-60ys
- M> F

AKA incisive canal cyst

29
Q

What is the presentation of Nasopalatine duct cyst?

A
  • Often asymptomatic
  • Pt may note salty discharge
  • Larger cysts may displace teeth or cause swelling in palate
  • Always involve midline but not always symmetrical
30
Q

Give the histology of Nasopalatine duct cyst

A
  • variable epithelial lining
  • Non keratinsed stratified squamous and modified respiratory
31
Q

What is the radiographic description of nasopalatine duct cyst?

A

PA/ Standard max occlusal
- Corticated radiolucency between/ over roots of central incisors
- often unilocular
- May appear heart shaped due to superimposition of anterior nasal spine

CBCT - needed for better visualisation and surgical planning

32
Q

How can you tell between incisive fossa or cyst?

A

Incisive fossa
- May or may not be vis on radiographs
- Midline oval shaped radiolucency
- Typ not visibly corticated

Consider transverse diameter
<6mm = incisive fossa
6-10 = consider monitoring
>10 = suspect cyst

33
Q

What is a Solitary bone cyst? Give AKA

A
  • Non odontogenic cyst without epithelial lining

AKA simple/traumatic/haemorrhagic bone cyst

34
Q

Give the incidence of solitary bone cyst

A
  • most common 20s
  • Male > Female
  • Mandible&raquo_space; Maxilla
  • Can occur in ass with other bone pathology e.g. fibro-ossesous lesions
35
Q

What is the clinical and radiographic presentation of Solitary bone cyst?

A

Clinical
- Asymptomatic and is an incidental finding
- Rarely pain or swelling

Radiology
- Majority in premolar/molar region of mandible (and non tooth bearing areas)
- Variable definition and cortication
- Scalloped margins giving pseudolocular appearance
- Project up between roots of adjacent teeth

36
Q

What is a Stafne cavity?

A
  • Not a cyst
  • Depression in the bone (with cortical bone preserved)
  • Only in mandible, exclusively lingual
  • Contains salivary or fatty tissue
37
Q

What is the incidence and presentation of stafne cavity?

A
  • 50 and 60yrs
  • Angle or post body of mandible
  • Inferior to IAC
  • Asymptomatic
  • Well defined, corticated radiolucency
  • Rarely displaces adjacent structures
38
Q

What biopsy can be done to obtain material for histology?

A

Aspiration biopsy (drainage contents)
Incisional biopsy (partial removal)
Excisional biopsy (complete removal)

39
Q

Give the radiographic features of a radicular cyst

A
  • Well defined
  • Round/oval radiolucency
  • Corticated margin continuous with lamina dura of non vital tooth
  • Larger lesions may displace adjacent structures
  • Long standing lesions - external root resorption and or contain dystrophic calcification
40
Q

Give the histological features of a radicular cyst

A
  • Epithelial lining often incomplete
  • Connective tissue capsule
  • Inflammation being present in capsule (variable inflammation)
  • Cholesterol clefts on the lining
  • Mucous metaplasia (epithelial cells become mucous secreting cells)
  • Hyaline/rushton bodies
41
Q

How does this balloon like growth occur in radicular cysts?

A
  • Epithelial rests of Malassez proliferates in PA granuloma
  • radicular cyst forms by either proliferating epithelium with central necrosis OR epithelium surrounds a fluid area
  • Continued growth of cyst by osmotic effect via semi-permeable wall and cytokine mediated growth
  • Bone resorption occurs interleukins activate osteoclastic activity
42
Q

What is a dentigerous cysts? Give the incidence

A

-Developmental odontogenic cyst
- Ass with crown of unerupted and usually impacted tooth
- Cystic change to dental follicle

Incidence
- Most common 20-40ys
- male > Female
- Mandible > Maxilla

43
Q

Give the radiographic features of dentigerous cyst

A
  • Corticated margins attached to cemento-enamel junction of tooth (larger may begin to envelope root of tooth)
  • May displace involved tooth
  • Tend to be sym initially and when gets larger cysts may expand unilaterally
  • Variable displacement of cortical bone (i.e. bony expansion)
44
Q

Give the histology of dentigerous cyst

A
  • Thin non keratinsed stratified sqaumous epithelium
  • Arise from reduce enamel epithelium, fluid acc and expanding cyst formation
  • May resemble radicular cyst if inflammed
45
Q

How do you distinguish between dentigerous cyst and enlarged follicle?

A
  • Normal follicular space 2-3mm
  • Measure from surface of crown to edge of follicle
  • Consider cyst if follicular space >5mm
  • Assume cyst if >10mm
  • Also consider cyst if radiolucency is asym
46
Q

What is an eruption cyst? What teeth is it ass with? What is the txt?

A
  • Variant of dentigerous cyst but conatined within ST instead of bone
  • Bluish translucent soft tissue
  • ASs with erupting tooth such as incisors - Children usually

TXT
- Small cut to allow to erupt
- No txt as not concerning

47
Q

What is an Odontogenic Keratocyst (OKC)? Give the incidence

A
  • Developmental odontogenic cyst (no specific relationship to teeth)

Incidence
- Most common 20-30yrs
- Male > Female
- Mandible > Maxilla 3:1
- Posterior > anterior

**BAD NEWS - Very high recurrence rate

48
Q

Give the radiographic signs of Odontogenic Keratocyst

A
  • Scalloped margins
  • 25% multilocular
  • Displacement of adjacent teeth (RR uncommon)
  • Characteristic expansion as it enlarges in medullary bone space before displacing cortical bone
  • Has sig mesio-distal expansion without bucco-lingual expansion
49
Q

What pre op diagnostic test is useful for OKC? What are the findings?

A

Cyst aspirate
- Contains squames
- Low sol protein content (<4g per decimeter)

50
Q

Give the histological features of OKC

A
  • Parakeratotic lining (majority of cysts don’t have keratin)
  • Basal palisading (uniform appearance)
  • Daughter cysts
  • Cell nests (retromolar)
  • No rete pegs and thin friable lining (epithelium separates easily so some can be left behind)
51
Q

What is the presentation of Basal Cell Naeuvus syndrome?

A
  • Multiple odontogenic keratocysts
  • Multiple basal cell carcinomas
  • Palmar and plantar pitting
  • Calcification of intracranial dura mater
  • Often at younger age (15yrs)
52
Q

For an aspiration biopsy what do you use? What fluid can be removed and what can they indicate?

A
  • Wide bore needle with 5-10ml syringe
    Can get
  • Air
  • Blood (may indicate Aneurysmal bone cyst)
  • Pus (Cystic lesion or infection)
  • Cyst fluid (clear straw coloured fluid in inflamm or devlopmentla cysts OR White or cream semi solid indicate keratocyst)
53
Q

What is the prupose and methodology of Incisional biopsy?

A

Purpose
- Obtain sample of lining for histopathological analysis

Methodology (under LA)
- Select place where lesion appears superficial
- Raise mucoperiosteal flap
- Remove bone as required
- Incise and rmeove section of lining

54
Q

Give the surgical options for cystic lesions

A
  1. Enucleation
    - All cystic lesion removed
  2. Marsupialisation
    - Creation of surgical window in wall of cyst , removing contents of cyst & suturing cyst wall to surrounding epithelium
    - Encourages cyst to decrease in size, followed by enucleation at later date
55
Q

Give advantages and disadvantages of enucleation

A

Advantages
- Whole lining examined pathologically
- Primary closure
- Little aftercare needed

Disadvantages
- Risk of mandib fracture with very larger cysts
- Dentigerous cyst and wish to presever tooth
- old age , ill health
- Clot filled cavity may become infected
- Incomplete removal may lead to recurrence
- Damage to adjacent stuctures

56
Q

What are the indications of Marsupialisation?

A
  • If enucleation would damage surrounding structures
  • Diff access to area
  • May allow eruption of teeth by dentigerous cyst
  • Elderly or medically compromised unable to withstand extensive surgery
  • Very large cysts , risk jaw fracture if enucleation
  • Can combine with enucleation at later procedure
57
Q

Give the advantages and disadvantages of Marsupialisation

A

Advantages
- Simple to perform
- May spare vital structures

Disadvantages/Contraindications
- Opening may close and cyst may reform
- Complete lining not available for histology
- Diff to keep clean and lots of aftercare needed
- Long time to fill in
- Need obturator to keep wound open

58
Q
A