Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Drugs > CYP450 isoforms > Flashcards

CYP450 isoforms Flashcards

1
Q

CYP1A2

A

Metabolise: theophylline, caffeine
Inhibited: cimetidine
Induced: tobacco, BBQ meat, cruciferous veges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

CYP2E1

A

Metabolise: ethanol, paracetamol
Induced: chronic ethanol comsumption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CYP2D6

A

Metabolise: debrisoquine, tricyclic antidepressants (amitriptyline), codeine
Inhibited: fluoxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CYP2C9

A

Metabolise: s-warfarin
Inhibited: cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

CYP2C19

A

Metabolise: omeprazole, clopidogrel
Inhibited: omeprazole (reducing metabolism of coadministered substrates)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CYP3A4

A

Metabolise: erythromycin, simvastatin, felodipine
Inhibited: ketaconazole, grapefruit juice
Inducted: rifampicin, St John’s wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Drugs (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions