CYP450 Enzymes ONLY

Question 1

Rifampin

Answer 1

3A4 inducer, 2C9 inducer, 2C19 inducer

Question 2

Name the 1A2 inducers (2 of them)

Answer 2

Omeprazole and tobacco smoke

Question 3

Name the 1A2 inhibitors (2 of them)

Answer 3

Furafylline and Fluvoxamine

Question 4

Name the substrates of 1A2 (3 of them)

Answer 4

Caffine, Theophylline, Tacrine

Question 5

% of 1A2

Answer 5

~15%

Question 6

% of 3A4

Answer 6

~30%

Question 7

Name the 2E1 inducers (2 of them)

Answer 7

Ethanol and isoniazid

Question 8

Name the 2E1 inhibitor

Answer 8

Disulfirma

Question 9

Name the 2E1 substrate

Answer 9

Chlorzoxazone