Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHA-2048 Pharmacocinétique Appliquée KKL > CYP > Flashcards

CYP Flashcards

1
Q

CYP responsables du métabolisme des rx

A

1A2
2B6
2C9
2C19
2D6
2E1
3A4
3A5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Inhibiteurs puissants 1A2

A

Ciprofloxacine
Fluvoxamine
Mexilétine
Propafénone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Inh puissants 2C9

A

Fluconazole
Fluvoxamine
Sulfaphénazole
Ritonavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Inh puissants 2C19

A

Fluvoxamine
Ticlopidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Inh puissants 2D6

A

Bupropion
Fluoxetine
Norfluoxetine
Paroxetine
Quinidine
Ritonavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Inh puissants 3A4

A

Ketoconazole
Itraconazole
Ritonavir
Indinavir
Clarythromycine
Erythromycine
Ciprofloxacine
Norfloxacine
Diltiazem
Norfluoxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ciprofloxacine est un inh puissant de…

A

1A2
3A4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fluvoxamine est un inh puissant de…

A

1A2
2C9
2C19

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ritonavir est un inh puissant de…

A

2C9
2D6
3A4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Norfluoxetine est un inh puissant de…

A

2D6
3A4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Medic métabolisés par 1A2

A

Antidépresseurs😭
Antipsychotiques😱

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Medic métabolisés par 2C8

A

Thiazolidinedione ( glitazone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Medic métabolisés par 2C9

A

AINS
ARA II
antidépresseurs 😭( fluoxetine)
Hypoglycémiants PO 🍬

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Medic métabolisés par 2C19

A

Antidépresseurs 😭
IPP 🍽️

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Medic métabolisés par 2D6

A

Antidépresseurs 😭
Antipsychotiques 😱
Analgésiques 🍑
Medic CV❤️

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Medic métabolisés par 2E1

A

Anesthésiques😴
Alcool 🍷

17
Q

Medic métabolisés par 3A4

A

1.Antidépresseurs 😭
Antipsychotiques 😱
Sédatifs hypnotiques😵‍💫
AB💊(sparfloxaxine,macrolides/ketolides)
Antiarythmiques ❤️
Analgésiques🍑
Antimalariens🦟
Antiparkinsoniens👋
Antirejet🚫
Inh calcique Ca
Inh non nucleosidiques de la transcriptase inverse
Inh protease ( antiviraux)🦠
Stéroïdes💉
Triptans😇
Statine
Antiepileptique
Antineoplasique

18
Q

Inh Pgp

A
  1. Amiodarone
  2. Ketoconazole
  3. Jus de pamplemousse
19
Q

Substrats Pgp

A
  1. colchicine
  2. Dabigatran etexilate (pro medic)
  3. Digoxin
    4.loperamide
20
Q

Ordre CYP en quantité

A

3A4/5/7
2C8/9/18
1A2
2E1
2D6 et 2C19

21
Q

Inducteur 3A4

A

Millepertuis
Rifampicine

22
Q

Inducteur 4A et B

A

Fibrates

PHA-2048 Pharmacocinétique Appliquée KKL (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions