CYP Flashcards

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1
Q

Inhibitors

A
Azole Antifungals (fluconazole, Posaconazole)
Clarithromycin/Erythromycin
Diltiazem/Verapamil
Amiodarone/Dronedarone
Fluvoxamine/Nefazodone
Grapefruit Juice

Inhibit the enzyme so the concentration of drug increases

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2
Q

Inducers

A
Carbamazepine/Oxcarbazepine/Eslicarbazepine
Phenytoin/Fosphenytoin
Phenobarbital/Primidone
Rifampin
St John’s Wort

Speeds up the enzyme = less concentration of drug

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