Cycle 1 - Evolution is happening Flashcards
Evolution
Change of a species over time resulting in biodiversity
HIV (human immunodeficiency virus)
It is a zoonotic disease, type of SIV (simian immunodeficiency virus) and retrovirus.
HIV hijacks immune cells. HIV goes through reverse transcriptase.
Can result in AIDS.
Retrovirus
a type of virus that transcribes RNA into DNA using reverse transcriptase therefore changing the genome of the cell
How to treat HIV
Antiviral drugs (prevent virus from replicating) - AZT
no vaccine
AZT
Blocks addition of more nucleotides and stops replication of the HIV genome by fooling the reverse transcriptase as AZT is very similar to thymine. After many months, HIV becomes resistant to AZT treatment.
Evolution of AZT resistance
Mistakes in copying the HIV genome results in mutation. Some variants are able to reproduce in the presence of AZT, some are not.