CVS Flashcards
Auto regulation of heart
1 Frank Starling law
2 Rate induced regulation Rate ~ force Ca 1)Increased Depolarisations 2)Increased Ca current per depolarisation cumulatively due to less time
Mechanisms of Frank Starling law
- increased Stretch ~ Increased Interaction between myofilaments
- Opens sensitive Ca receptors
- CICR
- increased Affinity of troponin C
Causes for sinus arrhythmia
1 autonomic activity
2 stretch reflex
3 Bainbridge reflex (stretches RA so AVN gets stretched )
4 irradiation from inspiratory centre( to vasomotor centre)
Immediate compensatory mechanisms for circulatory shock
1 Reflex activation eg, baroreflex, chemoreflex to contract vessels
2 circulatory fluid shift from interstitium
3 hormonal mechanisms
4 reverse stretch relaxation (vessels contract)
5 CNS mediated
Mechanisms of edema in heart failure
Via RAAS activation Water reabsorption
Via sympathetic GFR
Via stagnation Venous pressure
CPR used in
Cardiopulmonary resuscitation is used in cardiopulmonary shock
Variation of cardiac index with age
3.7 till 8
From 8 to 10 increase rapidly to more than 4 then decreases slowly to 2 at 70
Prominent a wave
- Pulmonary hypertension
- Pulmonary stenosis
- Tricuspid stenosis
- Myxoma of RA
- Atrial septal defect
- Cardiomyopathy
Canon wave
Giant a wave
RA beats against a closed tricuspid valve
1. Complete heart block
2. Nodal rhythm ( RA and RV contract simultaneously)
Absent a wave
Prominent v wave
Atrial flutter
Tricuspid regurgitation
Hepatomegaly and right heart failure
Due to hepatic congestion
Tender hepatomegaly is a feature of right heart failure