cvs Flashcards
% oxygentated blood that goes from mother to baby via umbilical vein
80%
clinical features of carcinoid syndrome
flushing diarrhea, cramps, n+v cough, wheezing, dyspnoea nodular liver owing to hepatic mets
four sites of baroreceptors
carotid sinus / aortic arch r atrium l atrium
6 x circulating hormones that cause vasodilation
adrenaline only in skeletal muscle / liver cgrp-alpha substance P histamine anp vip
ecg changes in hypokalemia
usually none, otherwise,
peaking p wave,
q-t not prolonged although u waves are mistaken as a lengthening of the t wave
flattening of t waves
serotonin found where
platetels chromaffin tissue in gut tissue in brain retina
4 x vasoactive substances released in carcinoid syndrome
serotonin bradykining and kallikreins prostaglandin histamine
atrial flutter ecg patter
sawtooth pattern, 200-350/min ventricular rate slowed by carotid pressure
function of atrial natriuretic peptide
protein in atrial muscle that naturally wants to get rid of water
serotonin derived from?
trytophan
two effects of histamine
dilates arteriorles increases vascular permeability
what is wpw syndrome?
additional aberrant muscular or nodal tissue connection, bundle of kent b/w atrai and ventricles
conducts more rapidlythan the slowly conducting AV node
4x features of congenital ventricular septal defect
pansystolic mummr increased pulmonary blood flow possibley late rvf poissibly late pulmonary hypertension
3 x stimulates for anp release
increase cvp, hr or immersion of body in water
4x ecg manifestations of WPW
short pr wide, slurred qrs normal pj interval paroxysmal atrial tachycardia
thromboxane a2 function
promotes platelet aggregation and vasoconstrictions - forms plug
6 x circulating hormones that cause vasoconstriction
adrenaline - except in skeletal muscle / liver na ang II na/k atpase inhibitor avp neuropeptide
serotonin functions x5
constriction of some vessels contraction of the ileum potentiates NA involved in vasospasm a/w migraine central neurotransmitter
@ birth, x3 things close
umbilical vein is cut, ductus venosus fetal lung expands, closure of foramen ovale aortic pressure increases, closure of ductus arteriosus
thromboxane a2 produced by?
common precursor arachnidonic acid via cox pathway
2 x types of kinins
bradykinin and lysylbradykinin
PGI2 prostacyclin produced by?
produced by endothelial and smooth muscle cells in vessels
kinins effects x4
increase capillary permeability chemotactic for leukocytes relaxtion of vascular smoothe muscle through NO contraction of visceral smooth muscle
prostacyclin PGI2 effects?
inhibits platelet aggregation and promotes vasodilation thus increasing flow
ecg changes in hyperkalemia
small p wave
prolonged pr interval
widening of qrs complex
peak t wave in precordial leads
vf