1
Q

Loop Diuretics
•Indications
•side effects
•3 trade names & their generic names/manufacturer/strength

A

•1)Acute pulmonary edema/edema
2) HF 3)HTN
4)chronic renal impairment
•Ototoxicity/headache/dizziness/weakness/orthostatic hypotension
• -Lasix (furosemide) , Sanofi الفه , 40mg
-Diusemid (furosemide), Hikma , 40mg
-Burinex (bumetanide), Leo زراعة ,1mg

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2
Q

Thiazide diuretics
•Indications
•Side effects
•3 trade names & their generic name/ manufacturer/ strength

A

•Edema / HTN / Hyperglycemia/ Glucose intolerant
•hypokalemia
•all hydrochlorothiazide
-Esidrex ,Novartis جردانه l25mg
-Modrex, United l 25mg
-Monozide, JPA |25mg

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3
Q

Potassium sparing diuretics
•Indications
•side effects
•adverse effects/toxicity
•2 trade names with there generic, strength and manufacturers

A

•1)primary aldosteronism
2)edema & HTN associated with HF
•headache dizziness weakness orthostatic hypotension
•1 Aplastic anemia
2 Thrombocytopenia
3 hyperkalemia ( nausea, vomiting, diarrhea, cramps, tachycardia then bradycardia)
• both spironolactone
-Aldacton 25-50mg Pfizer الصباغ
-Noracton 25mg JPA

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4
Q

ACEI
Indications
s/e
Contraindications

A

•-HTN -congestive HF
-kidney problems caused by diabetes
-improve survival after a heart attack
•cough & skin rash
•pregnancy & angioadema

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5
Q

ACEIs
•Capocard
•Capoten
•Angiotec
•Tritace
•Lisocard

A

•captopril 25/50 dar al dawa
•captopril 25/50 GSK طنوس
•enalapril 5/10/25 JPA الاردنية
•ramipril 2.5/5/10 Sanofi الفه
•lisinopril 5/10/25 dar al dawa

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6
Q

ARBs
Indications
S/e
Contraindications

A

•HTN/ congestive HF
•Back pain , dizziness, cold/flu like symptoms
•less than 1yo child & pregnancy

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7
Q

ARBs -sartan
•candesartan×3
•valsartan×2
•irbesartan
•Telmisartan

A

•1) Atacand 8/16 Astrazenecaامنيه
2)Blopress 8/16 hikma ابن سينا
3)Gradia 16 United
•1)Diovan 80/160 Novartis جردانة
2)Diostar 80/160 pharma international
•Aproval 150/300 Sanofi الفه
•Micaedis 40/80 boehringer Ingelhein شقير

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8
Q

Beta blockers
Indications
S/e
Contraindications(avoid use/use caution)

A

•mild to severe HTN / Angina pectoris / post acute MI
•usually well tolerated
Nausea/vomiting/ weight gain/worsening CHF
•-Avoid:
Heart block greater than 1 degree/sinus bradycardia/ cardiogenic shock
-Use caution:
Hyperactive airway syndrome (asthma or bronchospasm)

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9
Q

Beta blockers -olol
-Metoprolol
-Bisoprolol×2
-Atenolol
-Nebivolol
-propranolol
-carvidilol

A

-betaloc ZOK 50,100 Astrazeneca امنيه
-concor 2.5,5,10 Merck seronoنابلسي
-B-cor 2.5,5,10 joswe الوافي
-Tenormin 50,100 Astrazeneca امنيه
-NEBILET 5mg Menarini الشرق
-Inderal 10,40 Astrazeneca امنيه
-unidil 6.5,12.5,25 united

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10
Q

CCB (non-dihydropyridine)
Indications
S/e
Contra

A

•angina/mild to moderate HTN
•Headache/constipation
•complete heart block/HF

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11
Q

CCB (dihydropyridine)
Indications
S/e
Contra (avoid use with)

A

•Angina/ mild to moderate HTN”sustained release form”
•usually well tolerated
Headache/ dizziness /postural hypotension/perephral edema
•known hypertensivity/unstable angina/Lactation

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12
Q

CCB (non-dihydropiridine)
Virapamil
Diltazam

A

•isoptin 80,240 Abbot سختيان
•dilzam retard 90 Pfizer الصباغ

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13
Q

CCB (dihydropyridine) -dipine
•Nifedipine
•Amlodipine×2
•Felodipine
•Lecardipine

A

•Adalat 30,60 Bayerخوري
•Norvasc 5,10 Pfizer الصباغ
•Amlocard 5,10 الرام Ram
•Plendil 5,10 Astrazeneca امنيه
•Lercadip 10,20 algorithm اداتكو

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14
Q

Alpha blockers
•Indications
•s/e
-first-dose phenomenon
•contra:
-avoid use with
-use caution with

A

•mild to moderate HTN mostly diastolic/ BPH(due to vasodilater effect
•dizziness/fatigue/priapism,impotence/orthostatic hypotension
-syncope within 30min to 1hr, effect is transient, may diminish by giving at bed time.
•-prior sensitivity /hypotension
-impaired hepatic function/older adults.

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15
Q

Alpha blockers
•Prazosin hydrochloride
•Doxazosin

A

•minipress
•CARDURA 1,2,4mg Pfizer الصباغ

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