CVM Flashcards
CAUSES OF STE
- Acute pericarditis
- LV aneurysm
- Takotsubo
- Coronary vasospasm
- Normal variant angina (formerly known as Prinzmetal angina)
CABG indications
- Left main or Left main equivalent disease (proximal LAD + 2vessel OR 3 vessel disease)
- Multivessel disease + LV dysfunction
- High risk criteria on stress testing
- Angina refractory to medical therapy
Nitrate/Nitroglycerin c/i
- use of PDE5 inh
- Severe AS
- Hypertrophic CMO
- Inferior / posterior infarction (danger of hypotension)
Resting HR/BP for BB tx of chronic stable angina
HR 55-60
BP <130/80
Diabetic medication classes that benefit CAD
SGLT2 inh (empagliflozin - jardiance) \ GLP 1 agonist (liraglutide - victoza)
HCOM vs MVP murmur with Valsalva or Squatting to standing
HCOM - intensity increases
MVP - prolonged murmur (increases duration); mid-systolic click happens earlier
RV diastolic or RA systolic free wall invagination “collapse”
Failure of IVC to diminish or “collapse” during inspiration
Cardiac Tamponade
Most effective treatment of Constrictive Pericarditis
Pericardiectomy
Sometime can spontaneously resolve or respond to medical therapy with NSAIDs or prednisone
Treatment of recurrent Pericarditis
ASA / NSAIDs x 2wks + Colchicine x 3 mos***
EKG findings in Pericarditis
- diffuse STE
- PR segment depression
- Q waves don’t develop like they do in MI
Normal splitting of S2 is heard during ? Inspiration OR expiration
Inspiration
S2 splitting during both inspiration and expiration happens with what type of murmur
ASD
S2 splitting during expiration happens with what types of murmur
AS
HCM
Innocent murmurs in Pregnancy
Inc P2
S3
Early peaking systolic murmur over the upper left sternal border
Severe AS ECHO finding
indication for valve surgery?
valve area <1cm2
mean transvalvular gradient >40mmHg
SYMPTOMS ONLY
Severe AS PE findings
late peaking murmur
slow and delayed carotid pulse
murmur obscures A2
AR - valve replacement indications
Symptomatic
Progressive LV dilatation
LVEF <50%
Aortic coarctation is associated with what valve disease
Bicuspid Aortic Valve
Coarctation of Aorta PE findings
Diminished femoral pulses
HTN
Systolic murmur and may have diastolic component as well
Notching of post. ribs on CXR
Indentation of the aortic wall at the coarctation site.
Mitral Stenosis - med management
BB or CCB to control tachycardia and prolong diastolic filling
Coumadin for LA thrombus, AF, previous embolic event
Contraindications to Percutaneous mitral balloon commissurotomy treatment for rheumatic MS
LA clot
Significant MR
Significant valvular calcifications
AC?
- AF + mild AS
- AF + mod to severe AS
- NOAC depending on CHA2DS2-VASc
2. COUMADIN only regardless of CHA2DS2-VASc
Medications that can cause primary MR
Ergotamine (serotonin, dopamine, epinephrine A.)
Pergolide (dopamine R A.)
Cabergoline (dopamine R A)
Bromocriptine (dopamine R A)
3 Chronic MR surgery indications
Symptomatic but LVEF needs to be >30%
LVEF <60%
Progressive LV dilatation (>40mm) regardless of symptoms
Acute MR treatment
prior to SURGERY
- sodium nitroprusside MAP<60mmHg
- NE for hypotension
- intra-aortic balloon pump if unresponsive to therapy
JONES Criteria (acute Rheumatic Fever)
Group A strep infection/Elevated strep Ab titer PLUS
2 major OR 1 major +2minor
MAJOR J oints (mono or polyarthritis) ♥️carditis, valve damage Nodules (subcut extensor surf) Erythema marginatum (painless) Sydenham chorea
MINOR P olyarthralgia E EKG with PR prolongation A rthralgia C RP and ESR elevated E levated temp (T >38C)
Antibiotic of choice for acute Rheumatic Fever
Prophylaxis needed to prevent 2nd infection?
PNC
- NO CARDITIS: 5yrs or until 21 (whichever is longer)
- CARDITIS + NO RESIDUAL HEART DX: 10 yrs or until 21
- CARDITIS + RESIDUAL HEART DZ: 10 yrs or until 40
Perioperative AC management for mechanical aortic valve
Stop warfarin 5 days before surgery
Restart after surgery
When is INR goal 2.5-3.5 indicated
Mitral mechanical valve
Aortic mechanical valve + AF
Dec LVEF
Previous embolism
3 indications for ASD closure
- evidence of L–>R shunt with pulm flow : systemic flow ratio >1.5:1.0
- volume overload of right side
- symptoms
DAPT treatment in : NSTEMI with no stent placement
ASA81 + clopidogrel x 1 yr
then ASA indefinitely
DAPT treatment in : NSTEMI s/p PCI BMS
ASA81 + P2Y12 inh (clopidogrel 75mg qd or ticaglecor 90 mg BID) x 1 yr
then ASA81 indefinitely
Diagnostic study for Arrhythmia:
- infreq arrhthmias lasting 1-2mins
- activated by patient so poor choice for pt’s with syncope
Event monitor
Diagnostic study for Arrhythmia:
- EKG lead attached to pt
- saves previous 1-2 mis of EKG recorded when activated by pt
Loop recorder
Diagnostic study for Arrhythmia:
- long-term continuous EKG monitoring
- indicated for very infreq arrhythmias lasting 1-2 mins
Implanted recorder
AV nodal reentrant tachycardia tx
vagal maneuvers: -carotid sinus pressure -gagging or coughing -valsalva maneuver -immersing face in ice-cold water Medications: -adenosine (preffered) -metoprolol, esmolol, verapamil, diltiazem ABLATION is definitive treatment successful in 95% of cases
EKG findings: AV Reciprocating Tachycardia or WPW pattern
- short PR interval
- delta wave
- borderline or prolonged QRS complex
WPW pattern vs WPW syndrome
WPW syndrome is : WPW pattern + symptomatic arrhythmias involving the bypass tract
WPW (or AVRT) syndrome tx
- Hemodynamically unstable
- Narrow complex AVRT
- Wide complex, Irregular AVRT
- Drug resistant
- asymptomatic AVRT (WPW) conduction without arrhythmia
- Cardioversion
- Procainamide (class Ia Na channel blocker)
- Ibutilide (class III; delayed K channel blocker)
- Ablation
- -> Radiofrequency is more safer, more cost effective and less invasive than surgical ablation *** - does not require tx or investigation
Medications to avoid with WPW syndrome + AFib
CCB, BB, digoxin because can convert AFib to VT / VF
3 MC causes of A Flutter
Pulm disease exacerbation
Pericarditis
Following open heart surgery
A Flutter Mx
Cardioversion (hemodynamically unstable)
Radiofreq catheter ablation (superior to medical therapy)
Ascending thoracic aneurysm elective repair dimension
Descending thoracic aneurysm elective repair dimension
Ascending : ≥ 50-60mm
Descending : ≥ 60-70mm
Symptoms of hoarseness, dysphagia, back pain
Rapid growth >10mm/yr or >5mm/yr for Marfan and other congenital syndromes
Ascending thoracic aneurysm ECHO surveillance
ECHO surveillance if <50mm
<45mm : yearly
≥ 45 mm : q 6 mos
Treatment of aortic arch dissection
BB
Vasodilator (nitroprusside)
Which antihypertensive medication should be avoided in acute aortic dissection b/c it results in increased shear stress
Hydralazine
AAA screening cricteria
1 time screening for MEN ≥ 65 yo who have ever smoked
or who have never smoked but have higher family risk
AAA need for surveillance
4 - 5.4 cm follow up with US in 6-12mos
ABI
- ≤ 0.9
- ≤ 0.4
- ≥ 1.4
- 1 - 1.3
- PAD
- ischemic rest pain
- diabetes-related noncompressible calcified arteris
- normal
What to do if ABI is ≥ 1.4
toe-brachial index
claudication due to PAD vs spinal stenosis
spinal stenosis claudication occurs with walking, standing(resting). Only resolves when sitting or flexing (bending forward)
contraindication to use of Cilostazol
decreased LV EF
In the absence of active cardiac condition 2 pt situations that do not require preop cardiac risk assessment are
- low risk surgery (endoscopic, superficial breast, cataract, ambulatory)
- patient able to climb flight of stairs, walk on level ground at 4miles/hour ( ≥ 4 METs)
Omega 3 FA supplement decreases ?
Trig
Monounsaturated fats affect on HLD
Dec LDL
Either INC HDL or leaves it unchanged.
Large a waves and slow/blunted y descent
Tricuspid stenosis
Pulmonary stenosis
Pulm HTN
associated with Delayed atrial emptyting
Rapid x and y descent
Constrictive pericarditis
Cannon a wave
VTach or Complete heart block
atrium is contracting against closed tricuspid valve
Large a and large v waves
HF
IE prophylaxis requirement
Prosthetic heart valve ***
Previous hx of IE
Unrepaired cyanotic CHD
Repaired CHD with prosthetic material for <6mos post procedure
Cardiac transplant recipients who develop cardiac valvulopahty
Which procedures require prophylaxis for IE
Procedures on ….
Respiratory tract
Infected skin
Musculoskeletal tissue
Equal a and v waves with a single rapid x and attenuated y descent
Cardiac tamponade
-EKG findings of STE which quickly resolve
-Crescendo-type angina
-CE often normal b/c ischemia is of short duration
is consistent with ….
Normal variant angina (formerly known as printzmatel)
Normal variant angina tx (2)
CCB
Nitrates
to prevent vasospasms
Coccaine abuse + BB effect
Acute coccaine intox leads to hyperadrenergic state. BB block the beta component of these effects leaving unopposed alpha effect leading to adverse consequences
Thrombolytic therapy during cp benefits which type of EKG findings ? ***
And harmful for which type of EKG finding?
new LBBB > ant STEMI > inf STEMI
harmful if ST depression
Equalization of diastolic pressure are seen in (2)
Constrictive pericarditis
Cardiac tamponade
Indication for dipyridamole nuclear stress test (vs exercise treadmill test)
AFib
——-
Which electrolyte abnormalities cause prolonged QT (3)
HypoCa
HypoMg
HypoK
Anterior MI Anteroseptal Anterolateral Lateral Inferior Posterior
V2-4 V1-4 V4-6, I, aVL I, aVL II, III, aVF tall R in V1-2 and ST depression in V1-2
Pt with AFib on Coumadin undergoes PCI which is more appropriate? --cont warfarin alone --cont warfarin + ASA --cont. warfarin + P2Y12inh --cont. warfarin + DAPT
–cont. warfarin + P2Y12inh
4 components of Tetralogy of Fallot (TOF)
V-ROAR-V V--VSD RO--Right ventricular Outflow obstruction OA--Overriding aorta RV--Right Ventricular hypertrophy
NSTEMI pt blood thinner regimen
- ASA
- P2Y12 inh ticagrelor > clopidegrol
- parenteral AC :
- –>enoxaparin SC
- –>bivalirudin IV
- –>fondaparinux SC
- –>unfractionated hep (preferred with GFR < 20 or ESRD on dialysis patients)
Using antipsychotic in patient with prolonged QT interval increases the risk of
POLYMORPHIC VTach (torsades de pointes)
Indication for emergent Aortic Dissection for type B aortic dissection
Occlusion of major aortic branch leading to end-organ ischemia
Persistent HTN or pain
Class I indication for temporary transvenous pacing (5)
- asystole
- sxic bradycardia
- bilateral bundle branch block or alternating
- new or indeterminate age bifascicular block
- 2nd degree Mobitz type 2
Peri-operative mx
- -pt undergoing hernia repair
- -on warfarin for AVR with prosthesis
- -when discontinuing ASA/warfarin 5 Ds before the procedure do you bridge the patient?
NO
pulmonary valve stenosis - surgical indication
SEVERE pulmonary valve stenosis require
Balloon valvuloplasty or surgical valve replacement regardless of symptoms
Severe pulmonary valve stenosis findings
Late-peaking palpable systolic ejection murmur
Absence of ejection click
Features of RV pressure overload
Severe mitral stenosis (mean pressure gradient >10mmHg) + no symptoms + planning pregnancy … Mx ?
MV intervention
TEE use indications (4)
Endocarditis / Vegetation
Acute MR/AR
Aortic dissection
Prior to cardioversion for Afib/Aflutter
Which EKG lead shows ischemic changes first (or is looked at) during exercise stress test?
V5
7 EKG changes that create limitation to EXERCISE stress testing? From most concerning to least concerning
WPW, LBBB, paced rhythm LVH RBBB Digoxin Nonspecific ST changes
Contraindication to dobutamine nuclear imaging
Arrhythmia***
hyperTension
Contraindication to vasodilator (adenosine) nuclear imaging
Bronchospasms
Worsen AV block
If a patient is able to exercise but does not have normal resting EKG
Exercise with nuclear perfusion imaging
Treatment of choice for pts that can’t exercise and has contraindications to dobutamine or vasodilator nuclear imaging.
CT angiography OR
Coronary angio
Which pharmacologic stress test is preferred when pt has LBBB or paced rhythm
Vasodilator (adenosine, dipyridamole, regadenoson)
PCWP is a measure of
LA pressure which represents LVEDP
Pulsus paradoxus (inspiratory fall in systolic BP) seen in (3)
Pericardial tamponade
Asthma
Tension pneumothorax
Pulsus bisferiens (bifid pulse with 2 aortic peaks) seen in (2)
AR
HCM
PUlsus alternans (strong pulse weak pulse strong pulse) seen in (3)
Bigeminal PVCs
Severe LV dysfxn
Severe AS
JVP
Large a wave is seen with (3)
TS
Severe PS
Severe noncompliant RVH
Irregular Cannon a waves (a is contracting against closed TV)
A-V dissociation
- -> VT
- ->3rd degree AVB
- ->ventricular pacing in a pt with sinus rhythm and complete heart block
Rapid x and y descent
Constrictive pericarditis
Restrictive CMO
Rapid x descent with loss of y descent
Cardiac tamponade
Large v waves (RV contracts but TV is not entirely closed) - 2
RV infarction (w./ kussmaul sign) TR
How do you differentiate Constrictive pericarditis and
Restrictive CMO looking at JV pressure
Rapid x and y descent in both
Constrictive - Kussmaul sign and diastolic knock
Restrictive - no diastolic knock
In general during inspiration Right sided murmurs are louder…
Which Right sided murmur is SOFTER during inspiration?
Pulmonic Stenosis. which occurs with congenital pulmonic stenosis
Prognosis of CAD determined by these (3) factors
LV function
Exercise capacity < 4
Severity of angina
Most predictive RF for the presence of CAD
DM»_space; Active smoking
Which 4 groups benefit from statin
- clinica AS CVC (CAD, CVA, PAD)
- LDL ≥ 190
- LDL 70-189 + DM
- LDL 70-189 + 10 yr risk of ≥7.5%
Both 3 and 4 are ages 40-75yo
When to give Fibrinolytic therapy in a nonPCI facilitated hospital
If the PCI capable hospital is > 120 mins away
Symptom onset 12 hours
Indication for ICD implantation prior to discharge s/p STEMI
Sustained VT/VF > 48 hrs after STEMI
provided the arrhythmia is not due to transient ischemia, reinfarction, or electrolyte abnormality
Pulsus parvus et tardus in carotid pulse is commonly seen with which VHD
AS
Late systolic murmur at the apex
MVP
3 Holosystolic murmurs
MR
TR
VSD
Redundant tricuspid leaflet arising lower in the ventricle which makes RA appear huge +/- TR murmur
Ebstein Anomaly
– associated with WPW syndrome
- Murmur gets louder with valsalva for AS or HCOM
- Murmur gets softer with valsalva for AS or HCOM
- Carotid pulse has rapid upstroke and rapid downstroke- bifid
- Carotid pulse is delayed
- HCOM
- AS
- HCOM
- AS
3 BB shown to prolong survival in HF
Bisoprolol 10mg qd
Carvediolol 25mg bid
Metoprolol sustained release 150-200mg qd
In hypertrophic CMO does severity of LV outflow gradient correlate or increased with the risk of sudden death
NO; can correlate with the severity of disease
HCOM therapy goals
- slow down the heart HR50 with BB or verapamil
2. inc LV volume so it opens up outflow track
2 meds that inc risk of constrictive pericarditis
Procainamide
Hydralazine
Complication of recurrent Pericaditis
Constrictive pericarditis
Common causes of Constrictive pericarditis (6)
Idiopathic Post viral TB - in developing countries CTS Radiotherapy Coccidiomycosis
Kussmaul sign (insp rise in JVP) Large x and y descent Pericardial knock Calcification of pericardium Thickened pericardium is c/w
Constrictive Pericarditis
Gold standard test to differentiate between Constrictive Pericarditis and Restrictive CMO
RHC
F>M
Abnormal flow from Aorta to Right side of heart
Differential cyanosis
Continous machinery murmur
PDA
PDA surgical or percutaneous closure indications
Symptomatic
- -Coronaries that pass between the great vessels
- -Sudden death in exercising young ppl
- -can px with cp with exertion
Anomualous Coronary Arteries
Heart conditions that have absolute contraindication to Pregnancy (3)
Cyanotic CHD
Eisenmenger’s
Pulmonary HTN
2 causes of a pregnant pt ping with new onset Afib and Pulmonary edema
MS
Secundum ASD
6 Indications for ICD placement in HCOM patients?
–massive myocardial hypertrophy (wall thickness ≥30 mm)
–previous cardiac arrest due to ventricular arrhythmia
–blunted blood pressure response or hypotension during exercise
–unexplained syncope
–NSVT on ambulatory electrocardiography
–FHx of sudden death due to HCM
Which valve does not need long-term AC ?
Mechanical or
Bioprosthetic
Bioprosthetic