CV System Flashcards
CV system components
Heart, blood and blood vessels.
Right atrium
Receives blood from Inferior/Superior vena cava and coronary sinus. Holds -O2 blood. Has pectinate muscles which may aid contraction.
Left atrium
Receives blood from the PC via 2L/2R pulmonary veins. Has pectinate muscles as well.
Right ventricle
Has trabecular carnae. Papillary muscles anchor the chordae tendinae of the heart valve. -O2 blood.
Left ventricle
Thickest heart chamber bc myocardium needs to generate higher BP to force blood through SC. Has trabeculae carnae and papillary muscles.
Atrioventricular valves
Right AV = tri, left AV =bi. Locked between atria and ventricles.
Semilunar valves
At base of aorta and base of pulmonary trunk. Open when higher ventricular BP forces them apart.
Blood flow overview
RA - tri valve - RV - pul. valve - Pul trunk + arteries - Lungs - pul. veins - LA - bi valve - LV - aortic valve - aorta and systemic arteries - systemic capillaries
Depolarisation rates in SA Node, AV Node and AV bundle, bundle branches and Purkinje fibres
SA - 100/min
AV - 40-60/min
AV b,bb,Pf - 20-35/min
Autorhytmic Cell AP
No stable rm potential. Slow depolarisation as calcium has slow influx. Repolarisation due to efflux of potassium and Ca++ channels closing.
Cardiac contractile fibres
Stable rm potential of -90mV. Fast VG nA+ channels, plateau caused by opening of slow Ca++ channels. Repolarisation due to rapid efflux of K+.
Ca++ binding to troponin causes
Tropomyosin moves and allows the binding of actin and myosin.