CV Labs & Diagnostics Flashcards
what is Troponin an indicator of?
most sensitive indicator of myocardial damage
what does troponin differentiate between?
cardiac vs non cardiac chest pain
how long after an MI does a troponin elevate?
2-3 hours
when does a troponin level return to baseline?
10-14 days
what is the lab draw schedule for troponin?
initial occurrence, 12 hours, then daily for 3-5 days
What is a CK-MB?
an enzyme found primarily in the heart muscle, helps to diagnose an acute MI
how long is a CK-MD elevated after an MI?
3 hours
when does a CK-MD peak?
24 hours after MI
between a troponin and a CK-MB which is more specific to cardiac damage?
troponin
What does CRP indicate?
inflammatory illness
NONSPECIFIC
when does a CRP peak?
18-72 hours
if a CRP fails to normalize what may it indicate?
ongoing damage to heart muscle
how is a CRP useful?
monitors acute inflammation
when is a CRP not elevated?
with angina
What is a ESR used for?
nonspecific indicator of acute OR chronic infection, inflammation, or tissue infarction
how is an ESR useful?
monitors for chronic inflammation
What is a BNP the main source in?
cardiac ventricle
what does BNP aid in?
distinguishing between cardiac vs. respiratory causes of dyspnea
when are concentrations higher in a Pro-BNP?
Left ventricular dysfunction
levels are approximately fourfold higher than BNP concentrations
what is the main lipid associated with CV disease?
cholesterol
what are the two sources of cholesterol?
endogenous and exogenous
what affects cholesterol?
malnutrition
what are two types of lipoprotiens?
HDL,LDL
are lipoproteins an accurate predictor of heart disease?
yes
what is HDL’s job?
to remove cholesterol
HDL is good cholesterol
What is LDL’s job?
to deposit cholesterol in peripheral tissues
LDL “low down dirty” bad cholesterol
what is a normal cholesterol range?
150-200
<200 low risk of CAD
200-400 mod risk of CAD
>240 high risk of CAD
what is a normal range of triglycerides?
40-160
>190 high risk of CAD
What is a normal range of LDL?
<100
130-159 mod risk for CAD
>160 high risk of CAD
What is a normal range of HDL?
> 40-50
60 low risk of CAD
<40 high risk of CAD