CV Drugs PDA

Question 1

epinephrine bolus for:

moderate hypotension

circulatory collapse

Answer 1

• moderate hypotension: 10-100 mcg
• circulatory collapse: 1-3 mg

Question 2

epinephrine gtt dosage & receptors affected:

low, moderate, and high dose

Answer 2

• low (1-2 mcg/min): beta 2
• mod (4 mcg/min): beta 1
• large (10-20 mcg/min) beta and alpha 1

Question 3

dose & reconstitution for norepi gtt

Answer 3

1-20 mcg/min

or 0.05-2 mcg/kg/min (4mg in 250 mL)

Question 4

dopamine gtt dosage & receptors affected:

low, moderate, and high dose

Answer 4

• low (0.5-3 mcg/kg/min): D1
• mod (3-10 mcg/kg/min): beta 1
• high (>10 mcg/kg/min): alpha 1

Question 5

dobutamine gtt dose

Answer 5

2-10 mcg/kg/min

Question 6

ephedrine bolus dose

how is it diluted for admin?

Answer 6

2.5-10 mg

dilute 50mg in 10ml or 5ml

Question 7

phenylephrine bolus dose

Answer 7

50-100 mcg

(double dilute in 10ml)

Question 8

phenylephrine gtt dose

how is it reconstituted?

Answer 8

0.15-0.75 mcg/kg/min (dont need to know)

mix 10mg in 250 mL

Question 9

vasopressin bolus dose

how is it reconstituted?

Answer 9

0.5-1 unit

dilute 20 units in 20 mL

Question 10

vasopressin gtt dosage & reconstitution

what is considered low dose?

Answer 10

0.1-1 unit/min (40U in 100 mL)

low dose: 0.03-0.04 units/min

Question 11

infusion/loading dose of precedex

dose for awake crani

Answer 11

1 mcg/kg over 10 min, then 0.5-1 mcg/kg/hr

0.1-0.3 mcg/kg/hr

Question 12

milrinone bolus & gtt dose

Answer 12

bolus: 50 mcg/kg
gtt: 0.5 mcg/kg/min (0.375-0.75 mcg/kg/min)

Question 13

CaCl dose

Answer 13

250 mg - 1 g bolus over 10 min

Question 14

glucagon dose

Answer 14

1-5 mg IV

(Nagelhout says over 2-5 min)

Question 15

phentolamine bolus & gtt doses

how often are bolus doses given?

Answer 15

bolus: 5-10 mg Q 5-15 min (30-70 mcg/kg)
gtt: 1-10 mcg/kg/min

*PPT - for infiltration: 5-15 mg in 10mL*

Question 16

propranolol bolus dose and frequency

Answer 16

0.05 mg/kg (0.5-1mg) Q5 min

Question 17

metoprolol bolus dose

when is it given?

Answer 17

5 mg for HR > 80

2.5 mg HR 60-80

*titrate to HR 60-80 and SBP > 100*

Question 18

esmolol bolus & gtt doses

how is a gtt resconstituted?

Answer 18

bolus: 0.2-0.5 mg/kg

DL: 150 mg 2 min prior

gtt: 50-200 mcg/kg/min (2.5 g/250 ml)

Question 19

labetolol bolus and gtt doses

how is it reconstituted?

Answer 19

bolus 0.1-0.5 mg/kg

gtt: 2-8 mg/min (200 mg/200 mL)

Question 20

enalapril IV bolus dose

Answer 20

0.625-1.25 mg

Question 21

nicardipine gtt dosage

how is it reconstituted?

Answer 21

start at 5 mg/hr

increase by 2.5 mg/hr every 15 min to max 15 mg/hr

25mg/250 ml or 50 mg/250 ml

Question 22

diltiazem (Cardizem) bolus and gtt doses

how often are bolus doses given?

how is a gtt reconstituted?

Answer 22

bolus: 0.25 mg/kg over 2 min, repeat Q15 min
gtt: 5-15 mg/hr (125 mg/125 mL)

Question 23

nipride gtt dosage and max

how is the gtt reconstituted?

Answer 23

initial rate 0.25-1 mcg/kg/min

max 2 mcg/kg/min ?

gtt is 50 mg/250 mL

Question 24

nitroglycerin gtt dosage & reconstitution

Answer 24

up to 2 mcg/kg/min

25-200 mcg/min

50 mg/250 mL

Question 25

hydralazine bolus dose

onset?

Answer 25

10-20 mg IV

onset 10-20 min

Question 26

adenosine dosing

Answer 26

initial bolus - 6 mg

then 12 mg

then 18 mg

can repeat Q60 sec

Question 27

adenosine gtt for deliberate hypotension

Answer 27

5-50 mcg/kg/min up to 140-220 mcg/kg/min