CV Drugs

Question 1

Phenytoin

Answer 1

Class Ib

Question 2

Mechanism of Dobutamine

Answer 2

mostly Beta1 agonist

Question 3

Ibutilide

Answer 3

Class III (K channel blocker)

Question 4

Procainamide

Answer 4

Class Ia

Question 5

Adenosine

Answer 5

Agonist via A1 adenosine receptor at AV node, causes hyperpolarization

Question 6

Nifedipine

Answer 6

Class IV (Ca channel blocker)

Question 7

Which three adrenergic receptors do beta blockers act upon?

Answer 7

Beta1, beta2, and alpha1

Question 8

Quinidine

Answer 8

Class Ia

Question 9

Enalapril

Answer 9

ACE Inhibitor

Question 10

Metoprolol

Answer 10

Beta blocker

Question 11

Propafenone

Answer 11

Class Ic

Question 12

Mechanism of Dopamine

Answer 12

Endogenous precursor of NE - excerts its effects by directly stimulating adrenergic receptors as well as stimulating NE release

Question 13

Amiodarone

Answer 13

Class III (K channel blocker)

Question 14

Disopyramide

Answer 14

Class Ia

Question 15

Spironolactone

Answer 15

Aldosterone Antagonist

Question 16

Lisinopril

Answer 16

ACE Inhibitor

Question 17

Mechanism of Milrinone

Answer 17

Inhibitor of PDE, which inactivates cAMP to AMP resulting in more cAMP available to cell

Question 18

Encainide

Answer 18

Class Ic

Question 19

Valsartan

Answer 19

ARB

Question 20

Verapamil

Answer 20

Class IV (Ca channel blocker)

Question 21

Lidocaine

Answer 21

Class Ib

Question 22

Furosemide

Answer 22

Loop Diuretic

Question 23

Hydralazine

Answer 23

Vasodilator (arterial)

Question 24

Dofetilide

Answer 24

Class III (K channel blocker)

Question 25

Losartan

Answer 25

ARB

Question 26

Flecainide

Answer 26

Class Ic

Question 27

Acetazolamide

Answer 27

Carbonic anhydrase inhibitor (not used asa diuretic or in heart failure)

Question 28

Are ACE Inhibitors K sparing or K wasting?

Answer 28

K sparing - can cause hyperkalemia

Question 29

Isosorbide Dinitrate

Answer 29

Vasodilator (venous)

Question 30

Captopril

Answer 30

ACE Inhibitor

Question 31

Hydrochlorothiazide

Answer 31

Thiazide diuretic

Question 32

Mexiletine

Answer 32

Class Ib

Question 33

Are ARBs K sparing or K wasting?

Answer 33

K sparing

Question 34

Bumetanide

Answer 34

Loop Diuretic

Question 35

Bretylium

Answer 35

Class III (K channel blocker)

Question 36

Propanolol

Answer 36

Beta blocker

Question 37

Is digoxin renally or hepatically excreted?

Answer 37

Renally

Question 38

Which of the Class IV drugs has a greater effect on vascular (dilation) than cardiac effects?

Answer 38

Nifedipine (Dihydropuridines)

Question 39

Candesartan

Answer 39

ARB

Question 40

Sotalol

Answer 40

Class III (K channel blocker)

Question 41

What class of drug is equivalent to ACE-Is without the cough side effect?

Answer 41

ARBs

Question 42

Diltiazem

Answer 42

Class IV (Ca channel blocker)

Question 43

Digoxin mechanism

Answer 43

Slow down heart via Gi/o, also blocks Na/K ATPase causing intracellular accumulation of Na which can be exchanged for Ca via NCX increasing inotropy

Question 44

Torsemide

Answer 44

Loop Diuretic

Question 45

Metolazone

Answer 45

Thiazide - can be added to therapy if a loop diuretic produces insufficient diuresis

Question 46

Are aldosterone antagonists K sparing or K wasting?

Answer 46

K sparing