CV Diseases Flashcards
restricted perfusion of heart due to atherosclerosis
angina
pan or discomfort - tight, dull or heavy and passes within a few minutes
angina
pain that radiates to left arm, neck, jaw, back following exertion or stress
angina
relief: GTN or siblingual nitrate
angina
prophylaxis: aspirin, beta blockers, calcium channel blockers, long acting nitrates, ivabradine, nicorandil
angina
surgery: coronary bypass, PCI
angina
complications: heart attack, stroke, depression
angina
prevention: statins, ACEI, antiplatelets, lifestyle changes (to prevent MI/stroke)
angina
ischaemic necrosis of a tissue of myocardium secondary to occlusion/reduction of the coronary blood supply
acute MI
severe crushing, heavy, central chest pain
acute MI
pain radiating to jaw and arms, not relieved by GTN
acute MI
severe chest pain associated with sweating, nausea and vomiting
acute MI
caused by atherosclerosis of the coronary arteries
acute MI
treatment is MONA+C
acute MI
MONA+C
morphine (and anti-emetic), oxygen, nitrates, aspirin 300mg and clopidogrel 300mg
thrombolysis, PCI, CABG, angiogram
acute MI
complications: death, arrhythmia, aneurysm, inflammation, acute LVF, cardiogenic shock
acute MI
prevention - lifestyle changes
acute MI
low cardiac output from left side of heart (acute of chronic)
left heart failure
pulmonary oedema, orthopnoea, paroxysmal nocturnal dyspnoea
left heart failure
tachycardia, fine crepitations, pleural effusion more common in chronic, third heart sound, cardiomegaly and bat wing shadows in lower zones on CXR
left heart failure
caused by ischaemic heart disease, cardiomyopathy, valvular disease
left heart failure
diagnosed by natriuretic peptide test, echo, ECG
left heart failure
treated by lifestyle changes, loop diuretic, ACEI, beta blocker, aldosterone antagonist, digoxin
left heart failure
complications - arryhythmias, depression
left heart failure
IN ACUTE LVF
sit up, oxygen, IV furosemide, IV morhpine, but not in COPD
low cardiac output from the right side of the heart
right heart failure
peripheral oedema
right heart failure
ankle/sacral oedema, elevated JVP, hepatomegaly, ascites, normal CXR
right heart failure
often caused by LVF, cor pulmonale, congenital heart failure
right heart failure
diagnosed by natriuretic peptide tet, echo, ECG
right heart failure
treatment - lifestyle changes, loop diuretic, beta blocker, aldosterone antagonist, PCI
right heart failure
complications - arrhythmias
right heart failure
prevention - lifestyle changes, treatment of lung disease
right heart failure
acute onset of focal neurological signs and symptoms due to disruption of the blood supply (ischaemic or haemorrhagic)
stroke
face dropped on one side, weakness in one arm, speech may be slurred or garbled
stroke
sudden loss of vision, dizziness, difficulty swallowing, sudden and severe headache
stroke
caused by hypertension, hyperlipidaemia, smoking
stroke
diagnosed by CT and MRI, echo, carotid ultrasound
stroke
treatment - anticoagulant, vasodilator, statin, carotid stenosis
ischaemic stroke
treatment - haemotoma evacuation, craniotomy
haemorrhagic stroke
complications - DVT
stroke
intermittent claudication, critical limb ischaemia
peripheral arterial disease
hair loss, numbness, shiny skin, non-healing ulceration of feet and legs
peripheral arterial disease
caused by atherosclerosis of the peripheral arteries
peripheral artery disease
diagnosis - ABPI (ankle-brachial pressure index), doppler ultrasound, magnetic resonance angiogram
peripheral artery disease
treatment - exercise tolerance training, angioplasty and stenting, bypass/graft surgery, revascularistion, pain management, amputation
peripheral artery disease
complications - increased risk of MI/TIA
peripheral artery disease
infection of the endothelium of the heart valves, up to 25% mortality, acute or subacute
endocarditis
overwhelming sepsis and cardiac failure
acute endocarditis
fever, malaise, weight loss, tiredness, breathlessness
subacute endocarditis
Fever, Roth spots, Oslers nodes, Murmur, Janeway lesions, Anaemia, Nail haemorrhages, Emboli (FROM JANE)
endocarditis
predisposing factors - heart valve abnormality, calcification in the elderly, congenital heart disease, post rheumatic fever, IV lines, IV drug users, prosthetic heart valve
endocarditis
pathogenesis of endocarditis
heart valve damage > turbulent flow over roughened endothelium > platelets/fibrin exposed > bacteria settle and become microbial vegetations
3x blood cultures (before abx), echo
endocarditis
treatment - high dose IV abx
endocarditis
native valve, viridans strep endocarditis
benzylpenicillin and gentamicin
prosthetic valve, MRSA, enterococcus, staph epiidermidis
vancomycin and gentamicin
staph aureus
flucloxacillin
complications - infected vegetations break off and become lodged in next capillary bed > abscesses/haemorrhages (normally left side of heart)
endocarditis
prevention - abx prophylaxis
endocarditis
inflammtion of cardiac muscle, commoner in young people
myocarditis
fever, chest pain, shortness of breath, palpatations
myocarditis
arrhythmias, cardiac failure
myocarditis
caused by enteroviruses
myocarditis
supportive treatment
myocarditis
complications - heart failure, MI/stroke, arrhythmias
myocarditis
inflammation of pericardium, often occurs with myocarditis
pericarditis
chest pain is main feature, with fever, fatigue, nausea
pericarditis
pericardial rub
pericarditis
most commonly viral cause
pericarditis
symptoms, auscultation, ECG, CXR
pericarditis
treated with NSAIDs
pericarditis
complications - cardiac tamponade
pericarditis