Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CV 1 - Martin Pharm > CV ANS Drugs > Flashcards

CV ANS Drugs Flashcards

1
Q

Norepinephrine

A

a1=a2, B1»B2, Sympathomimetic (Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Epinephrine

A

a1=a2, B1=B2, Sympathomimetic (Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Isoproterenol

A

B1=B2»»a, Sympathomimetic (Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Phenylephrine

A

a1>a2»»>B, a-selective agonist, Sympathomimetic (Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Albuterol

A

B2»B1»»a, B2-selective agonist, Sympathomimetic (Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dopamine

A

D1=D2»B»a, Dopamine agonist, Sympathomimetic (Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Propranolol

A

B1+B2»>a, Nonselective B-Adrenergic Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Atenolol

A

B1»B2, B1-Selective B-Adrenergic Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Metoprolol

A

B1»B2, B1-Selective B-Adrenergic Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Phentolamine

A

a1=a2, Nonselective a-Adrenergic Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Prazosin

A

a1»»a2, a1-Selective a-Adrenergic Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Carvedilol

A

B1=B2>=a1>a2, Mixed Antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acetylcholine

A

Muscarinic and Nicotinic Agonist (Muscarinic Cholinergic Agonist) - very short acting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Bethanechol

A

M1-5»»Nm,Nn (Muscarinic Cholinergic Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Methacholine

A

M1-5»Nm,Nn (Muscarinic Cholinergic Agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Atropine (Oral, Parenteral, Ophthalmic)

A

M1=M2=M3»»Nm,Nn (Muscarinic Receptor Antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Ipratropium (Inhalation only)

A

(Muscarinic Receptor Antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Tiotropium (Inhalation only)

A

(Muscarinic Receptor Antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Parasympathetic Endings

A

Cardiac and smooth muscle, gland cells, nerve terminals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Sympathetic Endings

A

Sweat glands, cardiac and smooth muscle, gland cells, nerve terminals, renal vascular smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Cholinergic Nerves (ACh)

A

All Preganglionic to all ganglia, Post para, Post symp to sweat glands, Somatic muscle

22
Q

Adrenergic Nerves (NE)

A

Post symp to cardiac and smooth muscle, and gland cells (effector junctions)

23
Q

Adrenal Medulla

A

Symp leads to release of NE and E into circulation

24
Q

G Protein receptors

A

All adrenergic, All M Cholinergic - signal cascade

25
Q

Catecholamines

A

(5) Epinephrine, Norepinephrine, Isoproterenol, Dopamine, Dobutamine - metabolize quickly, not effective orally, do not penetrate CNS easily

26
Q

Dobutamine

A

B1>B2»a, B1-Selective Agonist, Sympathomimetic (Agonist)

27
Q

Non-catecholamines

A

Phenylephrine, Albuterol

28
Q

Alpha Adrenergic effects

A

Constrict blood vessels (a1>a2)

29
Q

Beta Adrenergic effects - B1

A

Inotropic (strengthen contraction) and chronotropic (increase rate)

30
Q

Beta Adrenergic effects - B2

A

Relax bronchioles and relax certain blood vessels

31
Q

Epinephrine as Prototype (a and B agonist) on HEART and Vessels

A

Increase heart rate, increase force of contraction, increase signal conduction, increase O2 consumption, increase work of heart.
Coronary vessel dilate and other constrict.

32
Q

Epinephrin reversal

A

Low dose activates B2 and causes vessel relaxation, high does activate a1 causing vessel constriction

33
Q

Epinephrine on BP (low dose - high dose behave like NE)

A

Systole increase and Diastole slight decrease, mean is same

34
Q

Epinephrine on smooth muscle

A

Bronchiole relaxation

35
Q

Epinephrine clinically

A

Pediatric Asthma (bronchodilater, vasoconstricter, inhibit histamine release via B2); anaphylactic shock

36
Q

Norepinephrine on Heart and Vessels

A

Positive inotropic (direct,) negative chronotropic (indirect,) vasoconstrict and increase BP

37
Q

Isoproterenol on Heart and Vessels

A

Increased HR and Force of contraction, vasodilate (increase systole and decrease diastole with overall decrease,) relax bronchioles

38
Q

Dopamine on kidneys

A

Vasodilate renal vascular beds

39
Q

Dobutamine effectiveness

A

Less than NE

40
Q

Phenylephrine on Vessels

A

Vasoconstriction, reflex bradycardia

41
Q

Phentolamine on Vessels

A

Decrease BP, reflex tachycardia

42
Q

Prazosin on Vessels

A

Decrease BP, less reflex tachycardia

43
Q

Propranolol Effects (Beta Blocker)

A

Decrease HR and CO, decrease conduction, decrease exercise tolerance, decrease depol, blocks dilation of vessels and blocks bronchodilation, decrease lipolysis and glycogenolysis

44
Q

Propranolol Clinical Uses

A

Angina (decrease CO and O2 demands,) HTN, Arrhythmias, post MI

45
Q

Atenolol

A

Blocks B1 WAY more than B2

46
Q

Muscarinic effects

A

Decrease spontaneous depol (neg chronotropy,) decrease conduction velocity, decrease atrial contractile strength, dilate vessels, contract bronchioles

47
Q

Muscarinic block

A

Atropine

48
Q

Ipratroprium

A

Can’t be absorbed across membranes, used for COPD

49
Q

Atropine Effects

A

Tachycardia, bronchodilation/relaxation

50
Q

Clinical Use of Antimuscarinics

A

Reverse reflex bradycardia

CV 1 - Martin Pharm (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions