Cutaneous And Subcutaneous Mycoses Flashcards

1
Q

Affect keratinized tissues

A

Cutaneous mycoses

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2
Q

Dermatophytes (keratinophilic)

A

Microsporon
Epidermophyton
Trichophyton

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3
Q

Causes ringworm/tinea

A

Dermatophytes (keratinophilic)

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4
Q

Ring-like appearance, red and scaly with a distinct margin, cordlike bumps beneath the skin fesembling a worm.

A

Tinea / Ringworm

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5
Q

Dermatophytes

A

Microsporum
Trichophyton
Epidermophyton

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6
Q

Microsporum infects

A

Skin, hair and rarely nails

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7
Q

Large, spindle pr cylinder shaped, thick walled, multi-septate, rough, spiny

A

Microsporum MACROconidia

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8
Q

Few or absent small, club shaped

A

Microsporum MICROconidia

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9
Q

Microsporum spp.

A

Microsporum audouinii
Microsporum canis
Microsporum gypseum

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10
Q

Anthrophilic

A

Microsporum auduoinii

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11
Q

Fluoresces under woods light (M. audouinii) color

A

Microsporum audouinii (yellow green)

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12
Q

Rice medium negative

A

Microsporum auduoinii

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13
Q

Salmon colored colonies

A

Microsporum audouinii

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14
Q

Fluoresces under woods light (M.canis) color

A

Bright yellow

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15
Q

Rice medium positive

A

Microsporum canis

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16
Q

Geophilic

A

Microsporum gypseum

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17
Q

No fluorescence

A

Microsporum gypseum

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18
Q

Rice medium positive

A

M. Canis
M. Gypseum

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19
Q

Cinnamon colored colonies

A

Microsporum gypseum

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20
Q

Trichophyton infects

A

Skin, hair, nails

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21
Q

Rare
Pencil shaped, multi-septate, thin walled, smooth borne singly on conidiophore

A

Tichophyton MACROconidia

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22
Q

Predominant
Spherical, tear shaped or clavate

A

Trichophyton MICROconidia

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23
Q

Trichophyton spp.

A

Trichophyton mentagrophytes
Trichophyton rubrum
Trichophyton tonsurans

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24
Q

Rose or epred-brown underside

A

Trichophyton mentagrophytes

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25
Q

Urease positive

A

Trichophyton mentagrophytes

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26
Q

Perforates hair

A

Trichophyton mentagrophytes

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27
Q

Star-shaped powder colonies

A

Trichophyton mentagrophytes

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28
Q

Microconidia in grapelike clusters

A

Trichophyton mentagrophytes

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29
Q

Deep cherry red or burgundy underside (enhanced on cornmeal or potato dextrose agar)

A

Trichophyton rubrum

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30
Q

Urease negative

A

Trichophyton rubrum

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31
Q

Does not perforate hair

A

Trichophyton rubrum

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32
Q

Tear shaped microconidia

A

Trichophyton rubrum

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33
Q

Tan or yellow rose with crater-like folds and wrinkled centers

A

Trichophyton tonsurans

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34
Q

Balloon shaped microconidia

A

Trichophyton tonsurans

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35
Q

Epidermophyton infects

A

Skin, nails, rarely hair

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36
Q

Club shaped, septate, thin-walled, smooth

A

Epidermophyton MACROconidia

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37
Q

Borne in slingles or cluster of 2-3 conidiophore

A

Epidermophyton MACROconidia

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38
Q

Absent

A

Epidermophyton MICROconidia

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39
Q

Epidermophyton spp.

A

Epidermophyton floccosum

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40
Q

Khaki colored colonies

A

Epidermophyton floccosum

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41
Q

affect deep layers of the skin, organisms found in soil thus feet usually affected, often result from a traumatic skin puncture from thorns or vegetation contaminated with fungi which are usually dematiaceous (darkly pigmented)

A

Subcutaneous mycoses

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42
Q
A

Fonsecaea pedrosoi
Fonsacaea compactum
Philaophora verrucosa
Cladosporium carrioniii
Exophiala jeanselmi
Exophioala spinifera
Wangiella dermatitidis

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43
Q

Chronic, non-healing, hard, warty, tumor-like lesions

A

Chromoblastomycosis

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44
Q

Characterized by cauliflower like lesions with SCLEROTIC BODIES” (copper-colored, septate cells)

A

Chromoblastomycosis

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45
Q

Chromoblastomycosis Characterized by cauliflower like lesions with

A

Sclerotic bodies

46
Q

Chromoblastomycosis
Types of (Sporulations)

A

Acrotheca
Phialaphora
Cladosporium

47
Q

Conidia in side

A

ACROTHECA:

48
Q

Conidia in cluster

A

PHIALAPHORA:

49
Q

CLADOSPORIUM

A

Conidia in chain

50
Q

Mixed sporation

A

Fonsecaea

51
Q

Phialaphora sporulation only

A

Phialaphora

52
Q

cladosporium only Chromoblastomycosis

A

Cladosporium

53
Q

Subcutaneous spp

A

Chromoblastomycosis
Phaeohyphomycosis
Mycetoma
Sporotrichosis or rose gardeners disease

54
Q

Phaeohyphomycosis other term

A

Alternaria, Bipolaris, Curvularia, Dreschlera, Exophiala, Phialaphora, Wangiella

55
Q

Opportunistic infections in subcutaneous

A

Phaeohyphomycosis

56
Q

Chronic granulomatous infection of the cutaneous and subcutaneous tissue and bone

A

Mycetoma

57
Q

Tumor-like deformities, abscesses, draining sinuses, granulomatous

A

Mycetoma

58
Q

Actinomycotic mycetoma:

A

Nocardia, Actinomadura, Streptomyces

59
Q

Eumycotic mycetoma:

A

Pseudoallescheria, Aspergillus, Exophiala, Acremonium, Curvularia, Madurella

60
Q

Sporothrix or

A

Rose garderners disease

61
Q

Sporotrichosis or Rose Gardener’s Disease
Caused by

A

Sporothrix schenkii

62
Q

Dimorphic fungus in subcutaneous

A

Sporothrix schenkii

63
Q

Sporotrichosis mold and yeast form

A

Mold form: narrow, septate hyphae with pyriform conidia arranged singly or in Flowerette arrangement

Yeast form: small, elliptoid budding, cigarette - shaped cells

64
Q

Colonies become _______ (enhanced on potato dextrose or cornmeal agar), wrinkled and leathery with age

A

Black

65
Q

Colonies become black (enhanced on potato dextrose or cornmeal agar), wrinkled and leathery with age

A

Sporotrichosis

66
Q

Usually infects farmers or florists
Introduced by trauma, usually to hand

A

Sporotrichosis or Rose Gardener’s Disease

67
Q

Types of tinea

A

Tinea capitis
Tinea barbae
Tinea corporis
Tinea crusis (jock itch)
Tinea Pedis (athletes foot
Tinea unguinum (Onchomycosis)

68
Q

scalp, eyebrows, and eyelashes

A

Tinea capitis

69
Q

smooth or glabrous skin (trunk)

A

Tinea corporis

70
Q

beard

A

Tinea barbae

71
Q

groin

A

Tinea Crusis (jock itch)

72
Q

Foot

A

Tinea pedis

73
Q

Nais

A

Tine unguium

74
Q

affects the hair and skin

A

Microsporum

75
Q

affects the skin and nails

A

Epidermophyton

76
Q

affects the hair, skin, and nails

A

Trichophyton

77
Q

Growth on rice medium

A

M. Canis
M. Gypseum

78
Q

Woods lamp fluorescence

A

M. Canis
M.auduoinii

79
Q

Abundant Red pigment

A

Trichophyton rubrum

80
Q

Positive in hair baiting test

A

Trichophyton mentagrophytes (v shaped penetration)

81
Q

“balloon-forms” aged microconidia; requires thiamine

A

Trichophyton tonsurans

82
Q

Trichophyton schoenleinii:

A

favic chandelier; favus tinea capitis

83
Q

Macroconidia: rare, 3-5 cells, thin- walled, “rat-tail”

A

Trichophyton verrucosum

84
Q

Favic chandeliers and chlamydospores are common

A

Trichophyton schoenleinii

85
Q

Swollen hyphae containing cytoplasmic granules

A

Trichophyton violaceum

86
Q

What kind of fungus Sporotrichosis? Morphology in yeast and mold form

A

Dimorphic

rosette/flowerette/daisy petal conidia

cigar- shaped

87
Q

Established infections appear as multiple, large, warty, <cauliflower-like= growths

A

Chromoblastomycosis

88
Q
  • Development of slow- growing verrucous nodules plaques
A

Chromoblastomycosis

89
Q

What kind of mold chromoblastomycosis

A

Dermatiaceous mold

90
Q

Chromoblastomycosis in tissue

A

In tissue: forms muriform cells (sclerotic bodies/Medler bodies) that are chestnut brown (copper pennies/black granule

91
Q

formation of abscesses that contain large aggregates of fungal hyphae known as granules or grains

A

Mycetoma

92
Q

Localized, chronic, granulomatous infections

A

Mycetoma

93
Q

Fungus-Like Bacteria

A

Actinomycotic

94
Q

composed of branching filaments, Gram-positive beaded rods

A

Granules (actinomycotic)

95
Q

composed of septate fungal hyphae either hyaline or dematiaceous; PAS and GMS positive

A

Granules (eumycotic)

96
Q

Subcutaneous Mucormycosis other name

A

Entomophthoromycosis

97
Q

from traumatic implantation of the fungus present in plant debris

A

Subcutaneous Mucormycosis (Entomophthoromycosis)

98
Q

Conidiobolus coronatus

A

(localized to the facial area mostly in adults)

99
Q

Basidiobolus ranarum

A

(proximal limbs in children)

100
Q

Hyphal fragments surrounded by intensely eosinophilic Splendore-Hoeppli material

A

Subcutaneous Mucormycosis (Entomophthoromycosis)

101
Q

Hyphal fragments are thin walled and poorly staining.

A

Subcutaneous Mucormycosis (Entomophthoromycosis)

102
Q

Require biopsy; histopathologic pictures are marked by focal clusters of inflammation with eosinophils and typical mucormycotic hyphae often surrounded
by eosinophilic Splendore-Hoeppli material.

A

Subcutaneous Mucormycosis (Entomophthoromycosis)

103
Q

rare infection caused by dematiaceous saprobes
which invade organs (skin, lungs, brain) of immunosuppressed hosts

A

Phaeohyphomycosis

104
Q

Phaeohyphomycosis
Cell wall pigmentation ranges from light to dark and may require special stains, such as the

A

Fontana-Masson melanin stain

105
Q

Black molds in culture

A

Phaeohyphomycosis

106
Q

Sporotrichosis causitive agent

A

Sporothrix schenckii

107
Q

Chromoblastomycosis causative agent

A

Fonsecaea (mixed sporulation)
Cladosporium (only cladosporium sporulation) Exophiala Cladophialophora
Rhinocladiella
Phialophora (only phialophora sporulation)

108
Q

Mycetoma causitive agent

A

Eumycotic
Exophiala
Phaeoacremonium
Curvularia
Fusarium
Madurella
Pyrenochaeta
Leptosphaeria
Scedosporium
Pseudallescheria boydii (most common)
Actinomycotic (Fungus-Like Bacteria)
Actinomyces
Nocardia

109
Q

Known as true fungi

A

Eumycotic

110
Q

most common mycetoma causative agent

A

Pseudallescheria boydii

111
Q

Subcutaneous Mucormycosis (Entomophthoromycosis) causative agent

A

Conidiobolus coronatus
Basidiobolus ranarum

112
Q

Phaeohyphomycosis causative agent

A

Exophiala jeanselmei
Wangiella dermatitidis
Bipolaris spp.
Alternaria spp.
Chaetomium spp.
Curvularia spp.
Phialophora spp. among others