current therapies Flashcards
1
Q
what are current immunosuppressive drugs and what parts of the immune system do they affect
A
corticosteroid - B and T cell function
Azothioprine: inhibits DNA synthesis (T and NK cell function affecred)
Cyclophosphamide: alkylating agent that interferes with DNA synthesis (B cell suppression and Ab production)
Cyclosporin and Tacrolimus: Tcell and NK cell
Sirolimus (rapamycin): IL-2 production by TH cells