csv-export (5)

Question 1

which drugs should you watch out with women taking OCPs who are taking antiepileptics?

Answer 1

carbamazepine, phenytoin, phenobarbital, topiramate?? interfere with OCP (should also use barrier)

Question 2

what do you tell women who have epilepsy and want to get pregnant?

Answer 2

change from valproate

Question 3

what is valproate? what does it do to __ drugs?”

Answer 3

carbamazepine, phenytoin, phenobarbital

Question 4

which antiepileptic drugs do valproate inc the toxicity?

Answer 4

carbamazepine, phenytoin, phenobarbital, topiramate, lamotrigine

Question 5

neonatal seizures?”

Answer 5

ethosuxamide? absence (ca channel blocker)

Question 6

what causes steven johnsons syndrome?

Answer 6

pretty much all AEDS?? sedation, dizziness, n/v, double vision, ataxia

Question 7

which AED is most famous for leukopenia?”

Answer 7

phenytoin!

Question 8

SEIZURE”

Answer 8

valproate

Question 9

SEIZURE”

Answer 9

valproate

Question 10

which drug causes decreased memory, renal stones, weight loss?”

Answer 10

topiramate

Question 11

which drug causes hyponatremia?”

Answer 11

carbamazepine

Question 12

which drug causes gingivial hyperplasia and tissue necrosis and arrhythmias with IV admin?”

Answer 12

phenytoin

Question 13

which drug causes antidepressant effect as well as AED?”

Answer 13

lamotrigine

Question 14

which drug can cause addition and hyperactivity?”

Answer 14

phenobarbital

Question 15

which drugs can cause ankle edema and weight gain?”

Answer 15

gabapentin and pregabalin

Question 16

which drugs have adverse psych effects?”

Answer 16

levetiracetam

Question 17

how is ketamine different from other IV anesthetics?

Answer 17

NMDA receptor antagonist, potent analgesic, and dissociative (hallucinations)

Question 18

propofol?”

Answer 18

all enhance GABA transmission

Question 19

if a person has liver disease, what do you give them?”

Answer 19

anxiolytics

Question 20

what is flamazenil? what can it lead to?

Answer 20

benzo receptor angatonist?? competitively inhibits benz on GABA

Question 21

ramelton? how does it work?”

Answer 21

benzo receptor agonist, bind to GABA that specificially modulate sleep

Question 22

which drugs work for sleep maintenance? sleep onset?

Answer 22

sleep maintenance?? eszopiclone and zolipidem

Question 23

what can clozapine cause?

Answer 23

agranulocytosis (its a second generation antipsychotic)

Question 24

what are 2 general side effects of all antipychotics?

Answer 24

delay cardiac conduction?? prolong QT?? risk for torsades de pointes

Question 25

which 2 drugs cause hyperprolactinemia?

Answer 25

haloperiod and risperidone

Question 26

side effects?”

Answer 26

MAOinhibitor?? used for atypical depression, MDD refractory to other tx, and anxiety

Question 27

side effects?”

Answer 27

SSRI

Question 28

side effects?”

Answer 28

SNRIs

Question 29

what kinds of drugs are amitriptyline, nortriptyline, imipramine?

Answer 29

tricylic antidepressants?? blocks 5?HT, NE transporters to inc NTS, blocks histamine and Ach receptors

Question 30

side effects of each”

Answer 30

bupropion: inhibits reuptake of DA and NE: MDD, smoking cessation, seasonal affective,