csv-export (5) Flashcards
which drugs should you watch out with women taking OCPs who are taking antiepileptics?
carbamazepine, phenytoin, phenobarbital, topiramate?? interfere with OCP (should also use barrier)
what do you tell women who have epilepsy and want to get pregnant?
change from valproate
what is valproate? what does it do to __ drugs?”
carbamazepine, phenytoin, phenobarbital
which antiepileptic drugs do valproate inc the toxicity?
carbamazepine, phenytoin, phenobarbital, topiramate, lamotrigine
neonatal seizures?”
ethosuxamide? absence (ca channel blocker)
what causes steven johnsons syndrome?
pretty much all AEDS?? sedation, dizziness, n/v, double vision, ataxia
which AED is most famous for leukopenia?”
phenytoin!
SEIZURE”
valproate
SEIZURE”
valproate
which drug causes decreased memory, renal stones, weight loss?”
topiramate
which drug causes hyponatremia?”
carbamazepine
which drug causes gingivial hyperplasia and tissue necrosis and arrhythmias with IV admin?”
phenytoin
which drug causes antidepressant effect as well as AED?”
lamotrigine
which drug can cause addition and hyperactivity?”
phenobarbital
which drugs can cause ankle edema and weight gain?”
gabapentin and pregabalin
which drugs have adverse psych effects?”
levetiracetam
how is ketamine different from other IV anesthetics?
NMDA receptor antagonist, potent analgesic, and dissociative (hallucinations)
propofol?”
all enhance GABA transmission
if a person has liver disease, what do you give them?”
anxiolytics
what is flamazenil? what can it lead to?
benzo receptor angatonist?? competitively inhibits benz on GABA
ramelton? how does it work?”
benzo receptor agonist, bind to GABA that specificially modulate sleep
which drugs work for sleep maintenance? sleep onset?
sleep maintenance?? eszopiclone and zolipidem
what can clozapine cause?
agranulocytosis (its a second generation antipsychotic)
what are 2 general side effects of all antipychotics?
delay cardiac conduction?? prolong QT?? risk for torsades de pointes
