Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CSO > CSO Study Guide > Flashcards

CSO Study Guide Flashcards

1
Q

Alimta (pemetrexed) drug class

A

Anti-cancer drug (“antimetabolite)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Alimta (pemetrexed) treats

A
  • met nonsquamous nonsmall cell lung cancer
  • malignant mesothelioma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

complications and side effects of pemetrexed can be reduced by using _____ and _______ supplementation

A

folic acid and vitamin B12 supplementation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Abraxane
(Paclitaxel protein bound) type

A

Anti-cancer drug (Cytotoxic /
Antineoplastic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Avoid __________ with Abraxane
(Paclitaxel protein bound)

A

grapefruit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Avoid _______ with Arsenic Trioxide (Trisenox)

A

Avoid/limit seafood and homeopathic remedies as these may contain arsenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Avastin (bevacizumab) type

A

Monoclonal Antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Bleomycin (Blenoxane) type

A

anti-cancer (antineoplastic/
cytotoxic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Carboplatin type

A

Anti-cancer drug (Cytotoxic /
Antineoplastic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Carbozantinib (Oral Pill) type

A

Targeted Therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

things to avoid / considerations with Carbozantinib (Oral Pill) type

A
  • Avoid grapefruits
  • don’t eat 2hrs before or 1hr after
  • take with 8oz H2O
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Cisplatin type

A

Anti-cancer drug (Cytotoxic /
Antineoplastic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cytoxan
(Cyclophosphamide/Neosar) type

A

Anti-cancer drug (Cytotoxic /
Antineoplastic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Avoid _______ , _______, and __________with Cytoxan
(Cyclophosphamide/Neosar)

A

Avoid grapefruit, starfruit, Seville oranges

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Etoposide (VP-16, Etoposide phosphate, Toposar, VePesid, Etopophos) is an _____________, ____________, and _________________.

A

antineoplastic / cytotoxic. Plant alkaloid and topoisomerase II inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Avoid _________ with Etoposide (VP-16, Etoposide phosphate, Toposar, VePesid, Etopophos)

A
  • AVOID pomegranate, seville oranges, grapefruit and star fruit
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Fluorouracil (Adrucil) AKA 5-FU type

A

Anti-cancer drug (Cytotoxic /
Antineoplastic)
“Antineoplastic”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Gemzar (Gemcitabine) type

A

Anti-cancer / antineoplastic / cytotoxic drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Avoid _______, ______, ______, ______, and ________ with Gleevec (Imatinib) * Oral Chemo

A

AVOID
St. John’s Wort, grapefruit, pomegranate, seville oranges and star fruit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Herceptin (Trastuzumab) type

A

Monoclonal antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Ifosfamide type

A

Antineoplastic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Avoid _________ with Methotrexate (Otrexup, Rasuvo, Rheumatrex, Traxall)

A

Do not take folic acid or B-vitamins w/in 24 hours of tx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Pembrolizumab (Keytruda) type

A

Monoclonal Antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Rituxan type

A

Monoclonal Antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Velcade (Bortezomib) * An injection * is a __________ therapy. More specifically, a ___________ ___________.

A

Targeted therapy. Proteasome inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Avoid _______, _______, _______, _______, and ________with Velcade (Bortezomib) * An injection *

A
  • AVOID
    green tea, grapefruit, pomegranate, star fruit, seville oranges
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Velcade (Bortezomib) * An injection * is used to treat

A

MM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Xeloda (Capecitabine) * Pill taken by mouth type

A

Anti-cancer drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Supplement _______________ with Xgeva

A

calcium and vitamin D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

FOLFOX =

A

Fluorouracil (5FU), Leucovorin (folinic acid), Oxaliplatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Black cohosh claims to __________ but may cause ______________

A
  • Suppresses symptoms (hot flashes) associated with menopause and breast cancer
  • Cause severe liver toxicity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Black cohosh may interfere with ________, __________, or __________

A

Tamoxifen, Doxorubicin, Docetaxel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

CoQ10 may reduce toxicity of _______ and ______ but can also interact with ____________.

A

Doxorubicin and carboplatin; warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

____________ may sensitize cisplatin resistant tumors to cisplatin

A

turmeric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q
  • DIM and I3c is a ___________
A

naturally occurring plant alkaloid metabolite ; found in cruciferous veggies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

This metabolite found in cruciferous vegetables may interfere with hormone treatment

A

DIM and I3c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

_____________ may enhance Tamoxifen through weak estrogenic activity

A

flaxseed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

___________ may interference with prescription drug saquinavor and antiplatelet meds

A

garlic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

___________ may help with nausea, heartburn, anorexia, diarrhea, and gas— however, it may also interfere with anticoagulant drugs

A

Ginger

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

___________ is one of the oldest living tree species. People use it reduce chemo-related toxicity; however, it may interfere with anticoagulant and anti-seizure meds

A

Ginkgo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Discourage use of _________ with alkylating agents, antitumor antibiotics and platinum analogues

A

Ginkgo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

_______________ may reduce inflammatory side effect of cancer treatment ie. may reduce degree of mucositis, stomatitis, esophagitis, and diarrhea

A

glutamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

____________ may interact with seizure meds, be converted to ammonia, and may decrease effect of lactulose

A

glutamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

_________ may inhibit drug metabolizing enzymes (like Bortezomib in myeloma)

A

green tea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

___________ is a Pacific island plant made into a beverage and holds concern for liver damage

A

Kava

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

__________ may enhance immune system but can also enhance tumor response

A

Reishi Mushroom

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

It is recommended to consume ____________ with caution in those taking tamoxifen, as this flavonolignan May interact with it.

A

silymarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

_______________ induces chromosome CYP3A4 resulting in lower plasma levels of drugs that are CYp3A4 substrates

A

St. Johns Wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

what should Regorafenib (Stivarga) be taken with and when?

A

a low fat meal and at the time each day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

grapefruit juice and St Johns wort can interact with _________________, which should be taken with a low fat meal and at the same time each day.

A

Regorafenib (Stivarga)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

What drugs are in folfox?

A

folinic acid (leucovorin), fluorouracil/5FU, and oxaliplatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

What drugs are in folfiri?

A

leucovorin calcium (calcium folinate), fluorouracil/5FU, and irinotecan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

What drugs are in folfirinox?

A

leucovorin calcium, fluorouracil/5FU, irinotecan hydrochloride, and oxaliplatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

_____________ is a topoisomerase I inhibitor that can cause severe diarrhea

A

Irinotecan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

____________ is an alkalizing agent used to treat colorectal and pancreatic cancers, and its primary side effect is cold-induced peripheral neuropathy

A

Oxaliplatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

__________ is a vinca alkaloid used to treat ALL, AML, sarcoma, brain, and thyroid cancers. Grape fruit and St. Johns Wort should be avoided with this medication.

A

Vincristine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Erlotinib/Tarceva type

A

Tyrosine Kinase Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

SIADH is a common side effect with __________ and ____________

(Hint: TV - SIADH)

A

vincristine and Erlotinib/Tarceva

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Turmeric should be avoided with this alkylating agent because it inhibits chemo-induced cell apoptosis

A

cyclophosphamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

5FU is an ___________________, meaning that it sabotages a cancer cell’s genetic code so that it can’t replicate and make more cancer cells

A

antimetabolite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

_____________ is a tyrosine kinase inhibitor used to treat GIST, leukemia, and MDS, and may interact with grapefruit

A

Gleevac (imatinib)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

Herceptin is a monoclonal antibody targeting ___________ and ________ genes

A

HER2+ and ERBB2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

________________ is a monoclonal antibody that treats breast and gastric cancer, but can also cause cardiotoxicity

A

Herceptin (trastuzumab)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

_____________, which is an antimetabolite, requires B12 and folic acid supplementation to minimize its side effects

A

Pemetrexed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

_____________ is a taxane that requires low fiber diet education for symptom management

A

Paclitaxel (Taxol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

______________ is an epipodophyllotoxin that can cause a metal taste during infusion and hypersensitivity reactions

A

etopiside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

Bortezumib (Velcade) is protein targeted agent that is used to treat __________ and _____________.

A

MM and mantle cell lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

No green tea is recommended with ______________ because some flavonoids and vitamin C presenting in green tea leaves and teas can neutralize it in the blood by direct interaction

A

Bortezumib (Velcade)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

_____________ is a vegetarian diet promoting natural, unrefined foods; eating 8x daily from allowed foods, combined with breathing exercises and enemas if tolerated

A

Budwig Diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

____________ is a natural diet and metabolic therapy promoting organic vegetarian diet with no sodium or fat except flaxseed oil including daily raw juices and strict adherence to meal schedule and prep

A

Gerson Therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

________________ is a metabolic treatment developed in 1970s combing vegetarian diet, mega doses of vitamins/minerals/digestive enzymes, and includes a vaccine made from a persons own urine or blood

A

Livingston Wheeler Diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

this diet claims that modern diets cause acidosis, which then causes disease by destroying minerals in cells and also claims cancer grows in acidic environments

A

alkaline diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

this diet is based on Budwig diet claiming cancer is caused by lack of oxygen in cells, weak immune system, excess acidity and toxicity mostly related to smoking, alcohol, and asbestos

A

Bill Henderson Protocol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

This diet claims that toxins from processed foods, pesticides, preservatives, and pollutants cause cancer so following diet modification which includes supplements, extracts of animal organs (pancreatic enzymes), and detox practices will cure cancer

A

Gonzalez Program

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

This diet is an adaptation of traditional Japanese diet and consists of an organic locally grown primarily vegetarian diet with whole foods

A

Macrobiotic diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

Health is promoted via balance in ying and yang for this diet

A

Macrobiotic diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

This diet claims that unprocessed foods preserve enzymes in food and provide health

A

Raw Food Plan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

The goal of _______________ is to lessen or ease symptoms of disease independent of curative efforts, and to improve QOL of patients and families facing problems associated with life threatening illnesses

A

palliative care

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

The goal of ________________ is to help someone live with a terminal illness as well as possible for as long as possible

A

hospice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

_____________ may increase risk for bleeding by way of omega 3 fatty acids role in decrease clotting and platelet aggregation

A

flaxseed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

____________ is an antidepressant medication that works in the brain to treat major depressive disorder, but is sometimes prescribed for nausea/vomiting, low appetite and underweight

A

Remeron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

T= reflects the size and extend of the tumor — explain T0 to T4

A

TX is tumor cannot be evaluated ; T0 is no evidence of tumor ; Tis is carcinoma in situ which means abnormal cells are present with no spread; T1 is tumor is not palpable or visible by imaging ; T2 confined to primary cancer site; T3 extends to neighbor tissue; T4 is metastatic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
83
Q

N= reflects extent of spread to local lymph nodes — explain each stage of N

A

a. NX regional nodes cannt be evaluated and N0 is no regional lymph node involved
b. N1 involvement of regional nodes
c. N2 etc. indicates # of nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
84
Q

_______, ________, and _________ are impacted during alcohol liver disease

A

Vitamin A, B-Vitamins (including B6), and folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
85
Q

_______, ________, and ________ are affected with renal failure

A

Vitamin B6, Vitamin C, folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
86
Q

On this religious diet, individuals follow plant based diet that excludes most animal products, alcohol, and caffeine

A

Seventh Day Adventist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
87
Q

____________ is described as metabolic disturbances that occur when large number of cancer cells are killed quickly leading to release of intracellular ions and metabolic byproducts into systemic circulation

A

Tumor Lysis Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
88
Q

Labs in Tumor Lysis Syndrome

A

Will see elevated potassium (>6), Phosphorus (>4.5), uric acid, and higher than normal BUN levels and LOW Calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
89
Q

How do we treat Tumor Lysis Syndrome?

A

i. Hydrate and recommend a low potassium, phosphorus, and purine diet
ii. Recommend insulin therapy, calcium carbonate, loop diuretic, and medication to clear uric acid (Rasburicase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
90
Q

______________ will present as water retention, less urine production, low Na levels, and lyte imbalances

A

SIADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
91
Q

____________ is a side effect of Alkylating agents: Cisplatin, Cyclophosphamide, Ifosfamide, and vincristine

A

SIADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
92
Q

What is the treatment for SIADH?

A

Fluid restrictions, hypertonic saline, medications that promote solute free water excretion by kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
93
Q

_____________ ____________ refers to a condition that secretes bioactive hormones, amines, and peptides. Specifically, they result in a secretion of excess serotonin

A

Functional NET

94
Q

___________ is a tumor marker for those diagnosed with NET

A

Chromogranin A

95
Q

___________ is a corticosteroid to help treat anorexia and early satiety

A

decadron

96
Q

______________ is an antihistamine prescribed to children to help treat anorexia and early satiety

A

Periactin

97
Q

___________ is a pro kinetic agent used to treat anorexia and early satiety

A

Reglan

98
Q

Miralax, lactulose, Milk of Magnesia, and Magnesium Citrate are examples of ______________ laxatives

A

osmotic

99
Q

two examples of stimulant laxatives are

A

dulcolax and senna

100
Q

________, _________, ________, and ________ are serotonin antagonists used to treat acute nausea (24 hours after chemo)

A

Zofran, Anzemet, Kytril, Aloxi

101
Q

__________ or _____________ are prescribed for prevention of nausea; ________ may be considered too.

A

Decadron or Zofran WITH neurokinin-1 receptor; reglan

102
Q

_______ , _________, _______, or ______ are prescribed for either anticipatory (before treatment) or delayed nausea and vomiting (1 to 7 days after chemo)

A

i. Dopamine antagonists= Compazine
ii. Benzemides= reglan
iii. Cannaboids= marinol
iv. Benezodiazapines= Ativan
**ATIVAN

103
Q

Describe the progression of the GVHD diet (just the phases)

A
  1. bowel rest –> 2. intro to oral –> 3. intro to solids –> 4. expansion of diet –> 5. Regular
104
Q

What are the symptoms of phase 1 of the GVHD diet? What is the diet intervention?

A

GI cramping, large volume diarrhea, low albumin, very short transit time, limited bowel sounds ; NPO, IV fluids, and meet protein/energy with nutrition support

105
Q

What are the symptoms of phase 2 of the GVHD diet? That is the diet intervention?

A

Minimal GI symptoms and <500mL diarrhea ; Isotonic, low residue, low lactose fluids

106
Q

What are the symptoms of phase 3 of the GVHD diet? That is the diet intervention?

A

Minimal to no GI symptoms with formed stool ; low lactose, fat, fiber, acid diet with no gastric irritants

107
Q

What are the symptoms of phase 4 of the GVHD diet? That is the diet intervention?

A

Same as phase 3 ; Shift from low to minimal and if fat malabsorption add low fat

108
Q

What are the symptoms of phase 5 of the GVHD diet? That is the diet intervention?

A

No cramping, normal stool, normal albumin ; Progress to reg with gradually adding lactose and fiber

109
Q

____________ is an Inpatient and outpatient screening tool and includes screening and assessment criteria

A

Patient Generated-Subjective Global Assessment (PG-SGA)

110
Q

_________ is purely a screening tool for inpatient and outpatient

A

Malnutrition Screening tool (MST)

111
Q

___________ is a screening tool which includes ECOG score for inpatient population only

A

Malnutrition Screening Tool for Cancer Patients (MSTC)

112
Q

______________ is a screening tool that contains screening and assessment (upper arm circumference measurement) and is for inpatient population only

A

Malnutrition Universal Screening Tool (MUST)
https://www.bapen.org.uk/pdfs/must/must_full.pdf

113
Q

Loss of subcutaneous fat can be identified by looking at …

A

orbitals, triceps, and fat over ribs

114
Q

Loss of muscle mass can be identified in …

A

temples, clavicles, shoulders, scapula, thigh, calf

115
Q

Malnutrition in CHRONIC ILLNESS non-severe

A

a. Energy intake- <75% for >/=1 month
b. Weight loss- 5% in 1 month, 7.5% in 3 month, 10% in 6 month, and 20% in 1 year
c. Physical finding- body fat, muscle mass, and fluid accumulation is mild, and reduced grip strength is N/A

116
Q

Malnutrition in CHRONIC ILLNESS severe

A

a. Energy intake- </= 75% for >/= 1 month
b. Weight loss- >5% in 1 month, >7.5% in 3 month, >10% in 6 month, and >20% in 1 year
c. Physical finding- body fat, muscle mass, and fluid accumulation severe, and grip strength measurable reduced

117
Q

Criteria for diagnosing cachexia

A

i. Weight loss of more than 5% over 6 months in absence of starvation
ii. BMI <20 with any degree of weight loss greater than 2%
iii. Skeletal muscle reflective of sarcopenia

118
Q

Protein needs in acutely or chronically ill older adult

A

@ least 1.0 to 1.2

119
Q

Adult with cancer protein needs

A

1.0 - 1.5

120
Q

Protein needs for an adult undergoing HCT

A

1.5

121
Q

Low Tyramine Diet

A

Avoid aged cheese, smoked/fermented/cured meats or fish, nuts,

122
Q

___________ or ________ can be prescribed to help treat dumping syndrome

A

octeotide or acarbose

123
Q

__________ does NOT increase as body fat increases

A

Nuclear factor-kappa beta (NFkB)

124
Q

A patient with Colon Cancer on Xeloda reports trialing the Budwig Diet to help fight the cancer. What supplement recommendation are you most likely to make?

A

Vitamin B6

125
Q

__________ is a chemotherapy used to treat hepatocellular cancer can cause anorexia

A

Doxorubicin (adriamycin)

126
Q

You are counseling a patient on Tarceva (Erlotinib), a tyrosine kinase inhibitor, who wishes to discuss the potential food / drug interactions. You recommend avoiding ________________

A

grapefruit and grapefruit juice

127
Q

The PG-SGA assesses _______, _______, and __________.

A

Percent weight change, dietary recall, and edema

128
Q

A patient on Cisplatin may experience ________, _______, and/or _______ side effects.

A

Dysesthesia (abnormal physical touch sensation without outside cause), SIADH, and/or dysgeusia

129
Q

A semi-elemental formula is a partially hydrolyzed formula used for individuals with _______________ that may be preventing standard enteral formulas to be digested or tolerated.

A

individuals with dysfunction in the GI tract

130
Q

Pernicious anemia is evaluated by looking at which lab values?

A

B12 and Folate

131
Q

__________, __________, and ________ are latent side effects of radiation therapy (RT).

A

osteoradionecrosis, hot flashes, and esophageal fibrosis

132
Q

Which botanical supplement was found to alter the pharmacokinectics the chemo drug Imatinib (Glivec)?

A

St Johns Wort

133
Q

A dietitian would best analyze a patient with hemolytic anemia with which lab(s) values?

A

RBC

134
Q

An isotonic, fiber-free formula is ideal for patients at high risk for ________________ or if they have _______________.

A

intestinal ischemia ; a high GFR

135
Q

______________ is a supplement originating from native Americans claimed to relieve pain and inflammation; however, in cancer care, it is also known to cause hepatotoxicity

A

Chaparral

136
Q

A patient starting on CHOP should increase ___________ intake

A

fiber

137
Q

___________ is the best tool to measure dysphagia

A

DIGEST

138
Q

A patient receiving Erbitux (cetuximab) will likely benefit from consuming foods that are good sources of _____________

A

magnesium

139
Q

Bisacodyl is a type of __________ ___________

A

stimulant laxative

140
Q

What is the soonest a G-tube can be removed when the patient has not used it for nutrition, hydration or medication and their weight has been stable?

A

4 weeks

141
Q

_____________ is used to control and relieve the symptoms of acute diarrhea

A

Loperamide

142
Q

_________________ is used to lower high cholesterol levels in the blood

A

Cholestyramine

143
Q

______________ is a brand of diphenoxylate and atropine. It’s a medication that treats diarrhea.

A

Lomotil

144
Q

Glutathione S-transferase is known as the _________ _________.

A

detoxifying enzyme

145
Q

Selenium is beneficial in reducing risk for which type of cancer?

A

Prostate

146
Q

Thrombocytopenia is characterized by a platelet count of <_____________________.

A

100,000

147
Q

You might suggest ____________ for someone on cisplatin

A

selenium

148
Q

What might the dietitian recommend be given with Cisplatin to reduce renal toxicity?

A

Mannitol

149
Q

At what creatinine level would Cisplatin be held?

A

1.5mg/dL

150
Q

Irinotecan is often provided with _______________for metastatic colon cancer.

A

Cetuximab (erbitux)

151
Q

Adriamycin (Doxorubicin) is often given with_______________for breast cancer.

A

Cytoxan (cyclophosphamide)

152
Q

__________ is a monoclonal antibody used as a treatment for breast cancer with side effects including thrombocytopenia.

A

Avastin (Bevacizumab)

153
Q

A common side effect of Mitomycin, an antibiotic used as a chemotherapy drug, is _______________.

A

renal and lung toxicity

154
Q

Cytarabine (Ara C or cytosine arabinoside) is a treatment for _________ __________ and is toxic to the ___________ and __________.

A

acute leukemias ; kidneys and liver

155
Q

GI perforation, hypertension, and CHF are common side effects of this anti-angiogenic treatment

A

Avastin (Bevacizumab)

156
Q

Xeloda is often given in replacement of ______________ for metastatic breast or colon cancers.

A

5FU (Leucovorin)

157
Q

It is recommended to not take ______________, a theopurine and antimetabolite, with dairy-containing foods.

A

Mercaptopurine (purinethol)

158
Q

_____________ may be given alongside FOLFIRI for colorectal cancer.

A

Cetuximab (Erbitux)

159
Q

__________________ is the most common side effect of Femara (Letrozole), a hormone therapy drug.

A

Nausea/Vomiting

160
Q

A person with Hodgkin’s Lymphoma is starting ABVD. What treatments comprise this regimen?

A

Adriamycin, Bleomycin, Velban, Dacarbazine

161
Q

Carboplatin (Paraplatin), Paclitaxel (Taxol), and/or Cisplatin (cis-platinum) may be offered alongside ________________ for non-small cell or small cell lymphomas.

A

Gemcitabine (Gemzar)

162
Q

Bone pain is a common symptom of this hormone receptor antagonist.

A

Lupron (Eligard)

163
Q

_____________ topoisomerase inhibitor (Top 1), is known to cause diarrhea, especially when paired with 5FU for the treatment of metastatic colon cancer.

A

Irinotecan

164
Q

FOLFOX is a first line treatment for which cancer?

A

Colon Cancer

165
Q

____________ has been studied to potentially enhance the benefits and reduced toxicity of Doxorubicin (Adriamycin)

A

Theanine

166
Q

This “chemotherapy protectant” is a derivative of folic acid and is often given alongside other treatments.

A

Leucovorin (5-FU)

167
Q

_____________ is a protein-targeted therapy and kinase inhibitor for renal cell cancer may cause fluid retention and decreased appetite.

A

Torisel

168
Q

Increasing evidence suggests at least ______ minutes per week of moderate exercise may prolong survival in those with a breast cancer diagnosis.

A

180

169
Q

The registered dietitian should monitor a patient’s _____________ to attain information on ongoing systemic inflammation.

A

CRP

170
Q

The dose of Warfarin a patient receives can be best determined by what lab value?

A

International Normalization Ratio (INR)

171
Q

In severe deficiency, each 1000IU dose increment of Vitamin D3 should increase 25-hydroxyvitamin D levels by:

A

10 ng/mL

172
Q

___________ and __________ have been found to assist in absorption of curcumin

A

black pepper and fatty foods

173
Q

______________ mushroom is not an immune modulating mushroom

A

Maitake

174
Q

As a dietary supplement, ________________ may exacerbate diarrhea due its laxative effect.

A

Aloe Vera

175
Q

Known otherwise as lockjaw, this is a possible late side effect of head and neck radiation therapy.

A

Trismus

176
Q

a patient may benefit from sucking on an ice pop or ice chips during infusion with 5FU or _________________.

A

Doxorubicin (Adriamycin)

177
Q

Caphosol is used to treat __________________

A

dry mouth and throat

178
Q

________________ is a medication that increases the saliva in your mouth to treat dry mouth as a result of Sjögren’s syndrome

A

Pilocarpine (Salagen)

179
Q

Questran (cholestyramine) is a medication used to …

A

lower high levels of cholesterol in the blood, especially low-density lipoprotein (LDL)

180
Q

________, ________, and _________ cancer survivors make up the majority of cancer survivors.

A

Prostate, colon, and breast

181
Q

Li-Fraumeni Syndrome is associated with an inherited defect in the _________ gene.

A

TP53

182
Q

Point mutations in genes which cause loss-of-function are termed ____________ genes

A

tumor suppressor

183
Q

What are two ways by which diet impacts epigenetics?

A
  1. Host somatic cell mitosis
  2. Germ cell trans generational inheritance
184
Q

____________ and ____________ are two types of epigenetic changes.

A

methylation and acetylation

185
Q

___________ ____________ is the scientific investigation of the composite interactions between nutrients, bioactive food components, and the genome as they impact host health and disease.

A

Nutritional genomics

186
Q

______________ are chemicals found in an organism, but not produced by it, such as drugs or pollutants.

A

Xenobiotics

187
Q

________________ are typically minor variations in nucleotide sequence that may impact the function of corresponding protein to varying degrees and thereby modify cancer risk.

A

Polymorphisms

188
Q

The ___________________ is a multisite randomized controlled trial that showed ~50% reduction in mortality rate for those who ate >5 servings of fruits and vegetables per day and exercised 30 minutes (moderate) 5-6 days / week.

A

Women’s Healthy Eating and Living (WHEL) Study

189
Q

Results from the initial _________________ suggested that a lifestyle intervention targeting dietary fat intake and weight loss could improve overall survival in breast cancer patients.

A

WINS study

190
Q

__________ describes muscle aches and pain

A

Myalgia

191
Q

_____________ describes joint stiffness

A

Arthralgia

192
Q

Evidence-based and concensus-driven cancer treatment standards of care are sanctioned by __________________

A

National Comprehensive Cancer Network (NCCN)

193
Q

What are the 6 subclasses of chemotherapy?

A

(hint: you want your patients to EAAAT V_ery much on chemotherapy)
1. Alkylating agents (like Cisplatin)
2. Antimetabolites (like Xeloda / capecitabine)
3. Antitumor antibiotics (like Adriamycin / doxorubicin)
4. Epiodophyllo-toxins (like etopiside)
5. Taxanes (like Taxol / paclitaxel)
6. Vinca alkaloids (like Vincristine / oncovorin)

194
Q

The 5 subclasses of biotherapy include:

A

(you skipped bio class to go party with MC PAC)
1. Monoclonal antibodies (like Rituxan / rituxumab)
2. Protein targeted therapies (like an mTOR inhibitor like affinitor)
3. Angiogenesis inhibitors (like Avastin / Bevacizumab)
4. Cytokines (like interleukin-2)
5. Cancer vaccine therapy (like Gardasil to protect again HPV)

195
Q

What are the 5 subclasses of hormone therapies?

A

(_S_argent PAAL is undergoing hormone therapy)
1. Selective Estrogen Modulators (SERMS) (like Tamoxifen)
2. Aromatase inhibitors (like aromasin)
3. Progesterone (like Megace)
4. Antiandrogens (like casodex)
5. Leutenizing hormone releasing hormone agonists (like Lupron)

196
Q

___________ ,________, __________, and ___________ are the 4 major cancer therapies.

A

chemotherapy, biotherapy, hormone, and radiation.

197
Q

frying, broiling, or grilling meats at high temperatures creates __________ and __________, who may increase cancer risk.

A

heterocyclic amines and polycyclic aromatic hydrocarbons

198
Q

when initiating PN, start is a goal of ______________% dextrose and titrate up as tolerated

A

25-50%

199
Q

_____________ is a chemotherapy that should also include increased fluid needs.

A

cisplatin

200
Q

What are 6 main indications for TPN?

A
  1. nonfunctional GI tract
  2. severe N/V
  3. severe diarrhea or malabsorption
  4. GI fistula
  5. severe acute necrotizing pancreatitis and unable to tolerate EN
  6. GVHD and intolerance to EN support
201
Q

what are 5 possible long-term complications of TPN?

A
  1. steatosis
  2. biliary sludge
  3. catheter sepsis
  4. venous thrombosis
  5. hypertriglyceridemia
202
Q

_________________ may allow bacterial and fungi overgrowth, which can cause pain when eating.

A

achlorhydria

203
Q

__________________, ________________, __________________, ___________, and ______________ are the most 5 most prevalent childhood cancers

A
  1. Brain and nervous system
  2. Lymphoma
  3. Leukemia
  4. Neuroblastoma
  5. Wilms Tumor
204
Q

Long-term side effects of childhood cancer include ___________, ________, ___________, and _______________.

A
  1. slow or stunted growth
  2. compromised bone health and development
  3. Altered eating behaviors
  4. Altered quality of life
205
Q

____________ and _____________ are the two vitamins/minerals of concern for childhood cancer survivors and can/should be supplemented.

A

Calcium and Vitamin D

206
Q

The 2 types of HCT are ____________ and ____________.

A

myeloblative and nonmyeloblative

207
Q

__________________ HCT involves high dose chemotherapy and radiation to ablate bone marrow

A

myeloblative

208
Q

_______________ HCT involves lower dose chemotherapy and radiation

A

nonmyeloblative

209
Q

What follows myeloblative or nonmyeloblative HCT?

A

an IV infusion of autologous (pt’s own), syngeneic (from an identical twin), or allogenic (from another human related or unrelated) stem cells.

210
Q

IV infusions of stem cells following myloblative or nonmyeloblative HCT preparations can come from __________, _________, or ___________.

A

bone marrow, peripheral blood, or umbilical cord blood

211
Q

A neutropenic diet should be followed for __________ months following HCT

A

3 months

212
Q

Symptoms of GI GVHD include __________, ___________, and ___________.

A

N/V, secretory diarrhea, and GI bleeding

213
Q

MNT for GI GVHD

A

low lactose, fiber, acid, fat, and then possibly ading PERT if nutritional interventions are not sufficient

214
Q

Chronic GVHD develops beyond ____________ days post-transplant.

A

80-100

215
Q

________________ therapy along with vitamin D and calcium supplementation with regular weight bearing exercise can reverse bone loss.

A

Bisphosphonate

216
Q

Eliminate _________ and _________ from TPN for persistent bilirubinemia

A

Copper and manganese

217
Q

ER+ and PR+ Breast cancer is treated with _________, _________, _________, and _________.

A

SERMs (tamoxifen), aromatase inhibitor (aromasin), ERDs (faslodex), and LHRHs (Lupron)

218
Q

_________, _________, ________, and __________ are the main risk factors for SCC of the esophagus, which usually is in the upper 2/3 of the esophagus.

A

smoking, ETOH, H Pylori, and HPV

219
Q

Risk factors for AE esophageal cancer, which usually occur in the lower 1/3 of esophagus, are __________ and ____________

A

GERD and Barrett’s esophagus

220
Q

_________ tubes are preferred to G-tubes in patients with esophageal cancer

A

J-tubes

221
Q

A right colectomy will resect the _______________ colon.

A

ascending colon

222
Q

___________, ______________, and ________________ are unique risk factors to salivary cancer

A

older age, radiation exposure, and asbestos exposure

223
Q

____________ is the most common lung cancer

A

NSCLC

224
Q

cigarette smoking, second hand smoke, gas exposure, ETOH, arsenic, chromium, and/or nickel exposure are risk factors for _______________

A

SCLC

225
Q

____________, ___________, and ____________ are gene mutations that increase ones risk of developing ovarian cancer

A

BRACA1, BRACA2, and RAD51C

226
Q

__________________ is the main chemotherapy classification for treatment of ovarian cancer

A

alkylating agents (like carboplatin)

227
Q

_________________ tumors represent 95% of pancreatic tumors

A

exocrine

228
Q

what is the overall survival rate of pancreatic cancer?

A

4% ; 5-10% if caught early and surgical resection is achieved

229
Q

Healthy eating patterns and physical activity can reduce _______% of the most common cancers

A

33

230
Q

According to AICR, people who consume red meat should consume no more than ______oz per week

A

16oz

231
Q

What nutrient may be used to enhance 5FU, as 5FU is targets enzyme that use this nutrient as a cofactor

A

Folate

232
Q

__________, _________, and _________ are allium veggies and protect against stomach cancer

A

garlic, onions, and leeks

CSO (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions