CSF, Ventricles and Meninges Flashcards
Ventricles lined with
Ependyma
Ependyma
Modified epithelium that produces CSF
The ventricular system is filled with
CSF
Ventricular system empties into
Subarachnoid space
CSF functions = 3
1) immune
2) autoregulation of cerebral blood flow
3) allow brain to float and reduce weight (1500 - 50g)
CSF produced by
60% choroid plexus
30% capillary seepage
10% water from metabolism
CSF = 7 points
1) It is an ultrafiltrate of plasma that diffuses passively through the ependyma-glial membrane lining the ventricles, passing through the extracellular spaces of the hemispheres, bathing neurons and neuroglia to diffuse out through the pia-glial membrane on the surface, and into the subarachnoid space
2) It ‘rinses’ the metabolic waste from the central nervous system through the blood–brain barrier
3) Its composition is similar to extracellular fluid - inorganic salts, 280-300 mosm/kg H2O; glucose, 50-80mg/dL; trace protein, 15-40mg/dL
4) Its total volume is 150ml, but its daily output is 550ml, therefore if circulation is blocked, pressure builds up rapidly
5) At any one time there is 30ml of CSF in the ventricular system and 100ml in the subarachnoid space
6) It accounts for 15% of brain volume
7) Cerebrospinal fluid also circulates through the ventricular system and the subarachnoid space before passing through the arachnoid villi, into the dural venous sinuses
Choroid plexus
network of blood capillary invaginated into ventricle, and site of CSF production
Layers of choroid plexus
capillary, pia and ependyma
Location of choroid plexus in each ventricle
These capillaries invaginate through the choroid fissure for the lateral ventricles, through the posterior wall of the 3rd ventricle and through the foramina of Luschka of the 4th ventricle
Each cerebral hemisphere contains
a lateral ventricle
Each lateral ventricle resembles
a C-shaped structure that begins at an inferior horn in the temporal lobe, travels through a body in the parietal lobe and frontal lobe, and ultimately terminates at the interventricular foramina where each lateral ventricle connects to the central third ventricle
Lat ventricle pos and ant horns
a posterior horn extends backward into the occipital lobe, and an anterior horn extends farther into the frontal lobe
A single midline 3rd ventricle is located
between the subcortical nuclei (in the diencephalon)
A single midline 4th ventricle
is located in the brain stem
Connecting the lateral ventricles with the 3rd ventricle are two
interventricular foramina (of Monro)
Between the 3rd & 4th ventricles runs
the aqueduct of Sylvius (passing through the midbrain)
Linking the 4th ventricle to the subarachnoid space are
two lateral foramina (of Luschka) and one median foramen (of Magendie)
3rd ventricle location and contents
This is a slit-like central chamber between thalami and hypotahalami of each hemisphere
Its contents are CSF and the choroid plexus
3rd ventricle roof
fornix