CSF Flashcards

1
Q

What is the normal pressure range of CSF in emH20?

A

5-20

This value indicates the normal intracranial pressure in a healthy individual.

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2
Q

What is the normal appearance of CSF?

A

Normal

Clear and colorless appearance is typical for normal CSF.

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3
Q

What is the normal protein level in CSF in g/L?

A

0.18-0.45

This range signifies normal protein concentrations in CSF.

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4
Q

What is the normal glucose level in CSF in mmol/L?

A

2.5-3.5

Glucose levels are typically maintained within this range in healthy individuals.

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5
Q

What is the expected CSF:Serum glucose ratio in normal conditions?

A

0.6

A ratio greater than 0.6 indicates normal glucose transport from blood to CSF.

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6
Q

What is the normal white cell count (WCC) in CSF?

A

< 3

This indicates a normal level of white blood cells in the CSF.

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7
Q

What are the characteristics of CSF in bacterial infections?

A
  • Pressure: > 30
  • Appearance: Turbid
  • Protein: > 1
  • Glucose: < 2.2
  • CSF:Serum Ratio: < 0.4
  • WCC: > 500
  • Predominant cells: 90% PMN

These features are indicative of bacterial meningitis.

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8
Q

What are the characteristics of CSF in viral infections?

A
  • Pressure: Normal or mildly increased
  • Appearance: Clear
  • Protein: < 1
  • Glucose: Normal
  • CSF:Serum glucose Ratio: > 0.6
  • WCC: < 1000
  • Predominant cells: lymphocytes

Viral meningitis typically presents with these CSF profile characteristics.

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9
Q

What are the characteristics of CSF in fungal/TB infections?

A
  • Appearance: Fibrin web
  • Protein: 0.1-0.5
  • CSF:serum Glucose: < 0.4
  • WCC: 100-500
  • Predominant cells: Monocytes

These findings suggest a fungal or tuberculosis meningitis infection.

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10
Q

Fill in the blank: The normal CSF glucose level is _______.

A

2.5-3.5

This is the expected glucose concentration in healthy CSF.

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11
Q

True or False: A CSF WCC of < 3 is considered normal.

A

True

This indicates a normal white cell count in the CSF.

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12
Q

What percentage of PMN is typically seen in bacterial infections?

A

90% PMN

A high percentage of polymorphonuclear leukocytes (PMN) is characteristic of bacterial meningitis.

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13
Q

What is the significance of the glucose CSF:Serum ratio being ___ in bacterial infections?

A

< 0.4

This low ratio indicates impaired glucose transport into the CSF, common in bacterial infections.

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