CSF Flashcards
how much csf do adults produce
20 mL per hour
where is the CSF produced
choroid plexuses of the two lumbar ventricles 3rd and 4th ventricles
where does the csf flow
subarachnoid space
where is the subarachnoid located
between arachnoid and pia matter
volume of csf in adults
90-150ml
volume of csf in neonates
10-60ml
how do the bodies maintain the fluid?
circulating fluid is reabsorbed back into the blood capillaries
where is the fluid being reabsorbed
arachnoid granulations/ villae
are capillary networks that form the CSF from plasma by mechanism of selective filtration under hydrostatic pressure and transport secretion
choroid plexuses
tight fitting structure of the endothelial cells in the choroid plexuses is termed
blood brain barrier
what is the procedure for obtaining CSF
lumbar puncture
what is the contraindication of this procedure
presence of infection at the pucnture site
how much volume of csf do we need for testing?
10-20ml
state the tubes for testing
chemistry serology
microbiology
hematology
additional tests
if the sample is only enough for one tube what must be tested first?
microbiology
tests are least affected by blood or bacteria introduced as a result of the tap procedure
chemical and serologic test
mode of preservation for chemical and serologic test
freezing
mode of preservation of sample for microbiology
room temperature
least likely to contain cells introduced by the spinal tap procedure
cell count
mode of preservation of the specimen for cell count
refrigerated
provides better exclusion of skin contamination
microbiology and additional serologic test
appearance of the csf specimen is normal (interpret)
crystal clear
csf appearance is hazy, turbid, milky, cloudy what are the possible causes?
wbcs
microorganism
protein
clinical significance of the csf specimen that is appeared to be hazy, turbid, milky, cloudy
meningitis
disorders that affect blood brain barrier
production of IgG within the CNS