CSF Flashcards

study

1
Q

function of the CSF

A

provides nutrients to the tissue, remove metabolic waste, provides mechanical barrier to cushion the brain and spinal cord agains trauma

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2
Q

The brain and spinal cord are lined in the?

A

meninges

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3
Q

What are the three layers of meninges

A

dura mater
arachnoid
pia mater

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4
Q

latin word for dura mater

A

hard mother

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5
Q

latin word for arachnoid

A

spiderweb-like

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6
Q

latin word for the pia mater

A

gentle mother

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7
Q

the outer layer that lines the skull and vertebral canal

A

dura mater

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8
Q

Thin membrane that lines in the surface of the brain and the spinal cord

A

pia matter

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9
Q

Filamentous inner membrane

A

arachnoid

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10
Q

CSF is produce by

A

choroid plexuses

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11
Q

how many mL of fluid does the adult does the adult produce every hour?

A

20 mL

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12
Q

normal volume of adult

A

90-120 mL

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13
Q

normal volume of neonates

A

10-60 mL

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14
Q

where does the fluid flow that is located between the arachnoid and the pia matter

A

subarachnoid spaces

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15
Q

the circulation fluid is reabsorbed back into the blood capillaries in the

A

arachnoid granulation

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16
Q

the capillary network that form the CSF from plasma by mechanism of selective filtration by hydrostatic pressure and active transport secretion

A

choroid plexuses

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17
Q

the endothelial cells have a tight fitting juncture the prevent the passage molecules. This tight fitting juncture is called?

A

blood-brain barrier

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18
Q

why is the blood brain barrier important

A

to protect the brain from the chemicals and other substances that circulating the brain

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19
Q

the disruption of the blood-brain barrier by diseases, such as meningitis and multiple sclerosis allows the ,,_ to enter the CSF

A

leukocyte, protein, and other chemicals

20
Q

the disruption of the blood-brain barrier by diseases, such as

A

meningitis and multiple sclerosis

21
Q

CSF is collected routinely by

A

Lumbar Puncture

22
Q

for chemistry and serology test

23
Q

For microbiology test

24
Q

for hematology and cell count

25
tubes that are frozen
tube 1
26
tubes that are refrigerated
tube
27
tubes that are at a room tempt
tube 2
28
excess fluid should be
frozen and not discarded
29
what is the specimen appearance if there are increase concentration of protein and lipids
cloudy milky turbid
30
what is the specimen appearance if there are presence of WBC
cloudiness
31
Termed used to describe CSF supernatant that is pink, orange, and yellow
xanthochromia
32
Very slight amount of oxyhemoglobin
pink
33
heavy hemolysis
orange
34
Conversion of oxyhemoglobin to unconjugated bilirubin
yellow
35
what is the cause of xanthochromia that is due to the immature liver function that is seen in the infants particularly premature infants
bilirubin
36
is an indicator of intracranial hemorrhage, but also it maybe due to the puncture of blood vessels during spinal tap procedure.
grossly bloody CSF
37
Normal appearance of the CSF
crystal-clear
38
what is the cause of the oily appearance of CSF
radiographic contrast media
39
fluid from traumatic tap can cause clots due to the?
plasma fibrinogen
40
associated with tubercular meningitis and can be seen after overnight refrigeration of the fluid
web-like pellicle
41
how many hours does the RBC's need to remain in the fluid before noticeable hemolysis
2 hours
42
what is dilution fluid of CSF
saline
43
use to lyse the RBC
3% glacial acetic acid
44
what is the stain that is add to the diluting fluid to stain the WBC
methylene blue
45
the speed of the cytocentrifuge should be checked monthly with
tachometer
46
the timing should be checked by
stopwatch