CSF Flashcards

1
Q

What are the three layers of meninges?

A

dura mater, arachnoid, pia mater

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2
Q

CFS is produced by the?

A

Choroid plexuses of the two lumbar ventricles and the third and fourth ventricles

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3
Q

In adults, approximately ______ of fluid is produced every hour

A

20 mL

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4
Q

What is the normal volume of CSF in adults?

A

90 to 150 mL

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5
Q

What is the normal volume of CSF in neonates?

A

10 to 60 mL

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6
Q

It reabsorbs the circulating fluid back into the blood capillaries at a rate equal to its production

A

arachnoid granulations/villae

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7
Q

They act as one-way valves that respond to pressure within the central nervous system (CNS) and prevent reflux of the fluid

A

Cells of the arachnoid granulations

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8
Q

These are capillary networks that form the CSF from plasma by mechanisms of selective filtration under hydrostatic pressure and active transport secretion

A

choroid plexuses

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9
Q

This is a very tight-fitting junctures that prevent the passage of many
molecules

A

blood–brain barrier

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10
Q

CSF is routinely collected by lumbar puncture between the?

A

third, fourth, or fifth lumbar vertebra

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11
Q

This tube is used for chemical and serologic tests because these tests are least affected by blood or bacteria introduced as a result of the tap procedure

A

Tube 1

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12
Q

This tube is usually designated for the microbiology Laboratory

A

Tube 2

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13
Q

This tube is used for the cell count because it is the least likely to contain cells introduced by the spinal tap procedure

A

Tube 3

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14
Q

A fourth tube may be drawn for the _____________ to better exclude skin contamination or for additional ____________.

A

microbiology laboratory & serologic tests, respectively

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15
Q

If it is not possible to perform tests STAT, the CSF specimen for hematology must be?

A

refrigerated

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16
Q

If it is not possible to perform tests STAT, the CSF specimen for chemistry and serology must be?

A

frozen

17
Q

If it is not possible to perform tests STAT, the CSF specimen for microbiology must be?

A

remained at room temperature

18
Q

It can be the result of an increased protein or lipid concentration, but also be indicative of infection

A

Cloudy, turbid, or milky specimen

19
Q

If only one tube can be collected, it must be tested first by?

A

microbiology

20
Q

It is not unusual for cell counts requested to be performed on both ______ and ______ to check for cellular contamination by the puncture

A

Tubes 1 and Tube 4. respectively

21
Q

It is a term used to describe CSF supernatant that is pink, orange, or yellow.

A

Xanthochromia

22
Q

The most common cause of xanthochromia is?

A

Presence of RBC degradation products

23
Q

A xanthochromic color due to a very slight amount of oxyhemoglobin

A

Pink

24
Q

A xanthochromic color due to heavy hemolysis

A

Orange

25
Q

A xanthochromic color due to the conversion of oxyhemoglobin to unconjugated bilirubin

A

Yellow

26
Q

Other causes of xanthochromia aside from RBC degradation include:

A

elevated serum bilirubin, presence of the pigment
carotene, increased protein concentrations,
melanoma pigment, and bilirubin
due to immature liver function

27
Q

This can be an indication of intracranial hemorrhage, but it may also be due to the puncture of a blood vessel during the spinal tap procedure

A

Grossly bloody CSF