CS Flashcards
What is the most common immunoglobulin in the blood?
lgG
What immunoglobulin has a pentamer shape?
IgM
What shape are most immunoglobulins?
Monomer
lgA can sometimes be a dimer
What is the function of lgG ?
Enhance phagocytosis of bacteria and viruses
Fixes complement and passes it to fetal circulation
Where is IgA found?
Predominant immunoglobulin found in breast milk
Also found also found in secretions of digestive, respiratory, urogenital tract and system
What is the function of lgM?
First immunoglobulin secreted in response to infection
What is the least common immunoglobulin?
IgE
What is the role of IgD?
B cell activation
What is the function of IgE?
Mediate type 1 hypersensitivity reactions
Provide immunity to helminths and parasites
Causes mast cell degranulation