crozer abx,bugs Flashcards

1
Q

augmentin

A

amoxicillin/calvulonic acid

500 or 875mg PO BID

clavulonic acid is 125 mg in 500 and 875 dose

PO abx outpt, polymicrobial

specturm- staph, strep, enterococci, gram -, anaerobes

NO pseudomonas, MRSA

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2
Q

zosyn

A

piperacillin/tazobactam

3.375 g IV q6h
renal dose 2.25g IIV q6h
alternate dose 4.5 g IV q6h

adult DM infection

spectrum- staph, strep, enterococci, gram -, anaerobes
YES pseudomonas
NO MRSA

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3
Q

augmetin dose

A

500 or 875PO BID

clavulonic acid is 125 mg in 500 and 875 dose

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4
Q

zosyn dose

A

3.375 g IV q6h
renal dose 2.25g IIV q6h
alternate dose 4.5 g IV q6h

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5
Q

unasyn

A

ampicillin/sulbactam

3.0g IV q6h
renal dose 1.6g IV q6h

use- polymicrobial DM infection

spectrum- staph, strep, enterococci, gram -, anaerobes

NO pseudomonas, NO MRSA

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6
Q

unasyn dose

A

3.0g IV q6h

renal dose 1.6g IV q6h

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7
Q

unasyn PCN allergy alternatives

A

clindamycin/cipro

levaquin

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8
Q

Timentin

A

ticarcillin/clavulonic acid

dose 3.1g IV q6h

broad spectrum polymicrobial woun

spectrum- staph, strep, gram -, anaerobes

YES pseudomonas
NO MRSA

watch increased Na

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9
Q

Timentin dose

A

dose 3.1g IV q6h

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10
Q

penicillins for pseudomonas

A

4th/5th gen

Zosyn (piperacillin/tazobactam)

Timentin (ticarcillin/clavulonic acid)

carbenicillin
mexlocillin
azlocillin

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11
Q

PCN alternative for PCN allergy pts

A

clindamycin/cipro

vancomycin

levofloxacin (Levaquin)

carbenicllin,
mezlocillin
azlocillin

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12
Q

PCN excretion

A

renal

Except
mezlocillin
azlocillin
piperacillin

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13
Q

PCN and probenecid

A

probenecid (gout rx) increase serum levels of PCN, cephalosporins

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14
Q

cephalosporins

A

probenecid (gout rx) increase serum levels

cross reactivity to PCN 1-10%

CI if PCN allergy- yes, esp if anaphylaxis
upset stomach only- may give, doc like heck

3rd gen cephalos- severe hospital gram - infection

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15
Q

tx severe hospital gram - infection

A

3rd gen cephalos

aminoglycoside (Rhocephin, gentamycin)

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16
Q

1st generation cephalos

A

gram + staph strep
NO MRSA

gram - PECKSS
proteus
Ecoli
Klebsiella
Salmonella
Shigella

anaerobes- NO bacteriodes

cefazolin (Ancerf)
cephalexin (Keflex)

17
Q

2nd gen cephalosporins

A

gram + staph, strep
NO MRSA

gram -  HeN PECKSS
h. influenza
Neisseria
Proteus
E Coli
Klebsiella
salmonella
shigella

cefaclor (Ceclor)
cefuroxime (Ceftin)

18
Q

3rd gen cephalosporins

A

gram + less than 1st, 2nd gen

gram - HeN PECKSS
PSEUDOMONAS

deftriaxone (Rocephin)
ceftazidime (Fortaz)
cefdinir (Omnicef)

19
Q

4th gen cephalosporins

A

gram + like 1st gen (staph strep)

gram- HeN PECKSS
PSEUDOMONADS

no anaerobes

cefepime (Maxipime)

20
Q

name cephalos of each generation

A

1st
cefazolin (Ancef)
cephalexin (Keflex)

2nd
cefaclor (Ceclor)
cefuroxime (Ceftin)

3rd