cross-sectional + ecological studies Flashcards
Lecture 3 content
what is the purpose of a cross-sectional study?
to estimate the frequency or outcome at a particular point in time.
what is a descriptive cross-sectional study?
describes frequency of exposure or outcome in a defined population.
what is an analytical cross-sectional study?
simultaneously collects information on both the outcome of interest and potential risk factors in a defined population.
then compare the prevalence of the outcome in the people exposed to each risk factor with the prevalence in those not exposed.
when would you use a cross-sectional study?
- Health service planning - prevalence of specific outcome in a defined population in time.
- useful for assessing burden of disease and planning preventative and curative services.
- generate hypotheses about causes
(association with current risk factors)
(association with past exposure of early clinical signs)
what are the methods used to collect data in cross-sectional studies?
- survey sampling
what are the 2 main sources of bias in cross-sectional studies?
- selection bias
- recall bias
how can bias be minimised in cross-sectional studies?
- can minimise by having strict case definition for the outcome of interest
- by using standardised methods of data collection
- by ensuring that the researcher who assigns the diagnosis is not aware of exposure status.
what are the advantages of x-sectional studies?
- easy and economical
- provides important info on the distribution and burden of exposures and outcomes - valuable for health-service planning
- can be used as the first step in the study of possible exposure-outcome relationship.
what are the disadvantages of cross-sectional studies?
- measures prevalence rather than incident cases - limited value for investigating etiological relationships
- can be difficult to establish the time-sequence of events in a x-sectional study.
- reverse causality
what is an ecological study?
an observational study with populations or groups (instead of individuals) being unit of observation.
compares group averages
- health
- risk factors
what are ecological studies used for?
- describing associations at a group level
- quick and cheap routine data
- generates hypotheses - first step
what is ecological fallacy?
an attempt to infer from the ecological level (group level) to individual level