Cross sectional Flashcards
Cross sectional
General info
Compares population on individual level.
- Snapshot of both Exposed and Diseased at one point in time (Prevalence)
Type: Descriptive & Analytic
Cross sectional
Advantages
- Common diseases. Prevalent & Long (Chronic)
- Multi diseases & exposures or risk factors can be assesed
- No loss to follow-up (Snapshot)
- Inexpensive. Little time to conduct
- Good for creating hypothesis
- Permit determination of population characteristics at given moment (Prevalence)
Cross sectional
Disadvantages
- Not useful for rare or short-term diseases (May not be captured in snapshot)
- Cannot establish causality
- Temporal relationship unclear (Dont know who came first between, cannot infer temporality because E and D measured simultaneously)
Cross sectional
Formula and interpretation
- Total prevalence of disease
(a+c)/(a+b+c+d)
- Total prevalence of exposed
(a+b)/(a+b+c+d)
- Prevalence of disease in exposed
a/(a+b)
- Prevalence of exposed in diseased
a/(a+c)
- Prevlence Odds Ratio (POR) ` (a/b)÷(c/d)`
- Prevalence Risk Ratio (PRR)
(a/a+b)÷(c/c+d)
Cross sectional
Prevalence Odds ratio (POR)
Describes if exposure is associated with odds of disease vs unexposed
Prevalence Odds Ratio (POR) ` (a/b)÷(c/d)
*
(a/b) odds of disease in exposed
*
(c/d)` odds of disease in unexposed
The odds of DEPRESSION among DRINKERS are 1.5 TIMES the odds of depression AMONG NON-DRINKERS
Interpretation of RISK ASSOCIATION:
* POR = <1 Exposure has asscn with low odds of disease vs unexposed
* POR = 1 Exposure not associated with odds of disease
* POR = >1 Exposure has asscn with high odds of disease vs unexposed
Cross sectional
Prevalence Risk Ratio (PRR)
It looks at the actual risk of getting the disease if you are exposed
Prevalence Risk ratio (PRR) (a/a+b)÷(c/c+d)
-
(a/a+b)
risk of disease in exposed -
(c/c+d)
risk of disease in unexposed
The risk of DEPRESSION among DRINKERS is 1.5 times the risk of DEPRESSION among NON-DRINKERS
Rare disease (<10% Prevalence) POR=PRR
Common disease POR>PRR
Interpretation of ACTUAL RISK:
* PRR = <1 Exposure associated with low risk (prevalence) of disease in exposed vs unexposed (Protective effect)
* PRR = 1 Exposure no effect (didnt prevent/harm)
* PRR = >1 Exposure associated with high risk (prevalence) of disease in exposed vs unexposed (Harmful effect)