Crohns Flashcards
more common in ___
males
where in the GI tract can crohns affect and where is it most common?
can affect any region of the GI tract from the mouth to the anus but most common in terminal ileum and colon
about 50% of people with crohns get _____ disease
perianal
what happens in perianal disease
- get Recurrent abscess formation
- Pain
- Can lead to fistula with persistent leakage
- Damaged sphincters
crohns symptoms are determined by the ___ of the disease
site
what are the sypmtoms of crohns in the small intestine?
- Abdominal cramps (peri-umbilical)
- Diarrhoea, weight loss
what are the sypmtoms of crohns in the colon?
- Abdominal cramps (lower abdomen)
- Diarrhoea with blood
- Weight loss
what are the sypmtoms of crohns in the mouth?
- painful ulcers, swollen lips, angular chelitis
what are the sypmtoms of crohns in the anus?
perianal pain, abscess
what may be found on clinical examination
- Evidence of weight loss
- RIF mass
- Perianal signs - inflammation at or near to the anus, including tags, fissures, fistulas , abscesses
what blood tests would you do?
FBC - may show anaemia, leukocytosis
CRP and ESR- high
platelets
iron studies - anaemia
what other tests would you do?
serum folate and B12 - may be low
stool testing
Metabolic panel
AXR
CT abdomen
MRI
what may be seen on AXR?
small bowel or colonic dilatation, calcification, sacroiliitis, intra abdominal abscess
what may be seen on CT
skip lesions, bowel wall thickening, surrounding inflammation, abscess, fistulae
get ____ ____ in 30-50% of people pathoogicaly
non-caseating granuloma
