Crohn's

Question 1

Principal Sx of UC

Answer 1

Diarrhea w/c is commonly bloody

Associated sx urgency or
tenesmus as it gets worse.

Colicky abdo pain due to constipation or loading

Toxic mega colon during severe flares

Inflammation spreads retrograde in a continous fashion

Question 2

Crohn’s is more heterogenous due to variation in dse location/extent. Sx include

Answer 2

Abdo pain
Diarrhea
Weight loss
Malaise
Anorexia 
Weight loss

Intestinal obstruction due
Strictures
Fistulae
Abscesses

Presentation based on location affected
Colitis with bloody diarrhea
Abdo pain
If ileal involved, RIF pain and obstructive sx

Small bowel involvement presentation
Weight loss
Nutritional deficiency
Malabsorption
Possibly fever

Question 3

IBD shares many Sc with other conditions

Answer 3

Such as IBS
Functional disorders
Infectious gastroenteritis including traveller’s diarrhea

Question 4

IBS Sx is longstanding with fluctuating severity but without alarm features or abnormal blood tests

Nocturnal sx suggestive gut inflammation.

Answer 4

Faecal calprictin is highly accurate in discriminating between IBS and IBD precluding the need for more intrusive and expensive test like colonoscopy and no alarm sx in younger low risks patients

Question 5

When thwere is diarrhea without blood or with or without evidence of malabsorption (iron, vitD, folate def)

What needs to be done?

Answer 5

Celiac dse should always be excluded as it is more common than IBD

Question 6

UC difference from crohn’s

Answer 6

Inflammation affects the colon only
Superficial layers affected and confined to the colonic mucosa
No granulomqs
No extracolonic dse
Continous retrograde beginning from rectum

Question 7

Crohn’s difference from UC

Answer 7

Anywhere mouth to anus
Discontinuous skip lesion
Transmural inflammation
Granulomas present
Abcesses
Fistula
Perianal dse

Question 8

In crohn’s relapse is confirmed by what?

Answer 8

Laboratory testing
Imaging
Coloniscopy

Question 9

In UC relapse is confirmed by what?

Answer 9

A flare symptoms which includes rectal bleedingwith an increase stool frequency
An
Bnormal mucosa at sigmoidoscopy

Question 10

When definitive distinction bet UC and CD after history, endoscopic appearance, histopathology of mucosal biopsies and radiology this condition is referred to as

Answer 10

IBD-U (unclassified IBD)

Question 11

Sx of infectious gastroenteritis (common) includes

Answer 11

Short-lived with an abrupt onset with sx at thier worst soon after starting

IBD has a more gradual, insidous onset with a cresendo or fluctuating pattern

IBD usually CD associated with weight loss. Anorexia the need to pass stool at night

Question 12

IBS is 50 times morr common than what?

Answer 12

IBD (10-15%) 0.3% for IBD

Question 13

IBD Sx

Answer 13

Weight loss
Elevated CRP
Nocturnal diarrhea
Blood stools
Fever
Obstructive sx
Anemia
Irondef
Low albumin