Crohn Disease Flashcards

1
Q

Farmer and associates classification of Crohn disease

A

on the basis of location alone - ileocolic, purely colonic, small bowel, and perianal

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2
Q

Vienna classification

A

categorizes disease on the basis of location, age of onset, and disease behavior

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3
Q

Vienna classification - location

A

terminal ileum (L1), colon (L2), terminal ileum and colon (L3), and any location proximal to the terminal ileum (L4)

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4
Q

Vienna classification - age of onset

A

less than 40 years of age (A1) and 40 years of age or older (A2)

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5
Q

Vienna classification - disease behavior

A

nonstricturing and nonpenetrating (B1), stricturing (B2), and penetrating (B3)

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6
Q

Crohn disease of the small bowel has the

A

highest recurrence rate

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7
Q

Abscesses

A

particularly common with ileocolic Crohn disease

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8
Q

Risk of colorectal cancer is approximately

A

three times higher in patients with Crohn disease than in the general population

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9
Q

Duodenal Crohn disease can lead to

A

gastric outlet obstruction, and in children can be mistaken for annular pancreas

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10
Q

When duodenal Crohn does not respond to medical therapy,

A

gastrojejunostomy with vagotomy is the preferred surgical treatment

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11
Q

Crohn disease of the SB is not common but associated with

A

one of highest overall recurrence rates

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12
Q

Two most prevalent strictureplasty technique:

A

Heineke-Mikulicz and Finney

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13
Q

Heineke-Mikulicz strictureplasty

A

best suited for strictures up to 5 to 7 cm long

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14
Q

Finney strictureplasty

A

best suited for strictures up to 10 to 15 cm long

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15
Q

Side-to-side strictureplasty

A

suitable for longer areas of stricture

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16
Q

Crohn disease is generally more severe on

A

the mesenteric side of the bowel

17
Q

Percent of patients diagnosed with Crohn disease that have ileocolic disease

A

~ 50%

18
Q

The most common fistulas associated with ileocolic Crohn disease

A

ileosigmoid

19
Q

Ileocolic Crohn disease is often associated with

A

intra-abdominal abscess or fistulas

20
Q

Colonic involvement is present in

A

29 to 44% of patients with Crohn disease

21
Q

Differentiation between Crohn colitis and ulcerative colitis can be difficult in the absence of

A

SB or anal disease

22
Q

Colonic Crohn disease appears to be more frequently associated with

A

cutaneous manifestations (e.g., pyoderma gangrenosum)

23
Q

The main indications for operative management of colonic Crohn disease are:

A

stricture, malignancy, side effect of medical therapy, and failure of medical therapy

24
Q

Toxic megacolon

A

any condition associated with colitis that is severe enough to result in sloughing of the colonic mucosa, thereby permitting endodoxins to enter the circulatory system and evoke a septic response

25
Q

Anal strictures pose

A

functional obstruction and lead to continuing problems with fistulas and suppurative disease

26
Q

Anal Crohn disease without stenosis

A

easier to treat medically - with metronidazole and anti-TNF Ab

27
Q

Mesalamine

A

reduces postoperative recurrence of Crohn disease

28
Q

Postoperative surveillance of Crohn

A

no clear guidelines at present

29
Q

Smoking affects

A

overall severity of Crohn disease - with smokers having a 34% higher recurrence rate and a higher rate of reoperation than nonsmokers